1006613-70-2

Basic information

• Product Name: 4-chloro-1-(4-chlorophenyl)-3,5-dimethyl-1H-pyrazole
• Synonyms: 4-chloro-1-(4-chlorophenyl)-3,5-dimethyl-1H-pyrazole
• CAS NO: 1006613-70-2
• Molecular Weight: 241.12
• Mol File: 1006613-70-2.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: 4-chloro-1-(4-chlorophenyl)-3,5-dimethyl-1H-pyrazole(CAS DataBase Reference)
• NIST Chemistry Reference: 4-chloro-1-(4-chlorophenyl)-3,5-dimethyl-1H-pyrazole(1006613-70-2)
• EPA Substance Registry System: 4-chloro-1-(4-chlorophenyl)-3,5-dimethyl-1H-pyrazole(1006613-70-2)

Safety Data

• Hazardous Substances Data: 1006613-70-2(Hazardous Substances Data)

Upstream product

• 1694-29-7 3-chloropentane-2,4-dione 
• 1073-69-4 N-4-chlorophenylhydrazine 

Downstream Products

• 1361143-46-5 3-[1-(4-chlorophenyl)-3,5-dimethyl-1H-pyrazol-4-ylthio]thieno[2,3-e][1,2,4]triazolo[4,3-c]pyrimidine 

Relevant articles and documents

Mixing with microwaves: Solvent-free and catalyst-free synthesis of pyrazoles and diazepines

A simple and facile condensation of hydrazines/hydrazides and diamines with 1,3-diketones/β-ketoester leads to the preparation of pyrazoles and diazepines in high yields. This eco-friendly protocol is accelerated by microwave heating and efficiently carried out without any reaction solvent or catalyst in as little as 5 min.

HBF4/ACN: A simple and efficient protocol for the synthesis of pyrazoles under ambient reaction conditions

An efficient and novel protocol for pyrazole synthesis has been developed by using fluoroboric acid as the acid catalyst. Simple and easily available 1,3-diketone and hydrazine derivatives are taken as the substrates for this purpose. The reaction entails

Cellulose sulfuric acid as a bio-supported and efficient solid acid catalyst for synthesis of pyrazoles in aqueous medium

A convenient and practical method was described for the regioselective synthesis of pyrazoles from hydrazines/hydrazides and 1,3-dicarbonyl compounds via the Knorr synthesis in water with cellulose sulfuric acid (CSA) as a biopolymer-based solid acid catalyst. Various hydrazines and hydrazides were reacted with 1,3 diketones and the desired pyrazoles were obtained in high yields. The reaction of less reactive hydrazines with 1,3-dicarbonyl compounds stopped at the corresponding hydrazone derivatives. Hydrazides were employed with β-ketoester, and imine adducts were the only isolated product. Simple isolation of products, mild reaction conditions, reusability of solid acid catalysts and short reaction times are advantages of this green procedure. This journal is