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Ganoderenic acid A is a triterpenoid compound originally isolated from Ganoderma lucidum, a traditional medicinal mushroom. It exhibits enzyme inhibitory activities, particularly as an inhibitor of β-glucuronidase with an IC50 of 0.12 mg/ml in rat liver microsomes. ganoderenic acid A has demonstrated hepatoprotective effects in a rat model of liver injury induced by carbon tetrachloride (CCl4), reducing the increases in serum aspartate aminotransferase (AST), alanine aminotransferase (ALT), and lactate dehydrogenase (LDH). Additionally, ganoderenic acid A inhibits aldose reductase by 54.2% at a concentration of 100 μg/ml.

100665-40-5

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100665-40-5 Usage

Uses

Used in Pharmaceutical Industry:
Ganoderenic acid A is used as a hepatoprotective agent for its ability to reduce liver injury induced by carbon tetrachloride (CCl4) in rats. It helps in lowering the levels of serum AST, ALT, and LDH, which are markers of liver damage.
Used in Enzyme Inhibition Applications:
Ganoderenic acid A is used as an enzyme inhibitor for its ability to inhibit β-glucuronidase, which plays a role in the metabolism of various compounds, including drugs and toxins. This inhibition can be useful in managing the activity of this enzyme in certain conditions.
Used in Diabetes Management:
Ganoderenic acid A is used as an aldose reductase inhibitor, which helps in managing diabetic complications by reducing the enzyme's activity. Aldose reductase is involved in the conversion of glucose to sorbitol, a process that can lead to diabetic complications when unregulated.

Check Digit Verification of cas no

The CAS Registry Mumber 100665-40-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,0,6,6 and 5 respectively; the second part has 2 digits, 4 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 100665-40:
(8*1)+(7*0)+(6*0)+(5*6)+(4*6)+(3*5)+(2*4)+(1*0)=85
85 % 10 = 5
So 100665-40-5 is a valid CAS Registry Number.
InChI:InChI=1/C30H42O7/c1-15(10-17(31)11-16(2)26(36)37)18-12-23(35)30(7)25-19(32)13-21-27(3,4)22(34)8-9-28(21,5)24(25)20(33)14-29(18,30)6/h10,16,18-19,21,23,32,35H,8-9,11-14H2,1-7H3,(H,36,37)/b15-10+/t16?,18-,19+,21?,23+,28+,29-,30+/m1/s1

100665-40-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name (E)-6-[(7S,10S,13R,14R,15S,17R)-7,15-dihydroxy-4,4,10,13,14-pentamethyl-3,11-dioxo-2,5,6,7,12,15,16,17-octahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-methyl-4-oxohept-5-enoic acid

1.2 Other means of identification

Product number -
Other names Lanosta-8,20(22)-dien-26-oic acid,7,15-dihydroxy-3,11,23-trioxo-,(7beta,15alpha,20E)

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:100665-40-5 SDS

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