1006708-91-3 Usage
Uses
Used in Pharmaceutical Synthesis:
(R)-(p-CF3)3-t-BuPHOX is used as a chiral ligand in the pharmaceutical industry for the synthesis of chiral molecules with high enantiomeric excess. Its high selectivity and reactivity make it a valuable asset in the development of new drugs and the improvement of existing ones.
Used in Agrochemical Synthesis:
In the agrochemical industry, (R)-(p-CF3)3-t-BuPHOX is employed as a chiral ligand for the production of enantiomerically pure agrochemicals. This ensures the desired biological activity while minimizing potential environmental and health risks associated with less selective compounds.
Used in Natural Product Synthesis:
(R)-(p-CF3)3-t-BuPHOX is utilized as a chiral ligand in the synthesis of complex natural products, enabling the creation of enantiomerically pure compounds with potential applications in medicine, fragrances, and other industries.
Used in Asymmetric Catalysis Research:
(R)-(p-CF3)3-t-BuPHOX is used as a chiral ligand in academic and industrial research for the development of new asymmetric catalytic processes. Its high selectivity and reactivity make it an attractive candidate for exploring novel reaction pathways and improving existing synthetic methods.
Overall, (R)-(p-CF3)3-t-BuPHOX is a versatile and effective chiral ligand with a wide range of applications across various industries, particularly in the synthesis of chiral molecules with high enantiomeric excess. Its unique structural features and performance in asymmetric catalysis have solidified its position as a valuable compound in chemical synthesis and medicinal chemistry applications.
Check Digit Verification of cas no
The CAS Registry Mumber 1006708-91-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,0,6,7,0 and 8 respectively; the second part has 2 digits, 9 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1006708-91:
(9*1)+(8*0)+(7*0)+(6*6)+(5*7)+(4*0)+(3*8)+(2*9)+(1*1)=123
123 % 10 = 3
So 1006708-91-3 is a valid CAS Registry Number.
1006708-91-3Relevant academic research and scientific papers
A general enantioselective route to the chamigrene natural product family
White, David E.,Stewart, Ian C.,Seashore-Ludlow, Brinton A.,Grubbs, Robert H.,Stoltz, Brian M.
experimental part, p. 4668 - 4686 (2010/08/13)
Described in this report is an enantioselective route toward the chamigrene natural product family. The key disconnections in our synthetic approach include sequential enantioselective decarboxylative allylation and ring-closing olefin metathesis to form the all-carbon quaternary stereocenter and spirocyclic core present in all members of this class of compounds. The generality of this strategy is demonstrated by the first total syntheses of elatol and the proposed structure of laurencenone B, as well as the first enantioselective total syntheses of laurencenone C and α-chamigrene. A brief exploration of the substrate scope of the enantioselective decarboxylative allylation/ring-closing metathesis sequence with fully substituted vinyl chlorides is also presented.
