100677-64-3

Upstream product

• 70-23-5 ethyl Bromopyruvate 
• 1576-35-8 toluene-4-sulfonic acid hydrazide 

Downstream Products

• 136035-38-6 Ethyl indole-3-<2-(4-toluenesulphonylhydrazono)>propionate 
• 136035-30-8 Ethyl 1-(toluene-4-sulphonyl)-4a-methyl-4,4a,9,9a-tetrahydro-1H-pyridazino<3,4-b>indole-3-carboxylate 
• 136035-28-4 Ethyl 6-hexyl-1,4,5,6-tetrahydro-1-(toluene-4-sulphonyl)-pyridazine-3-carboxylate 
• 136035-27-3 Ethyl 4,4a-5,9b-tetrahydro-1-(toluene-4-sulphonyl)-1H-indeno<3,2-c>pyridazine-3-carboxylate 
• 136035-25-1 Ethyl 6-phenyl-1,4,5,6-tetrahydro-1-(toluene-4-sulphonyl)-pyridazine-3-carboxylate 
• 136035-26-2 Ethyl 4,4a-5,9b-tetrahydro-1-(toluene-4-sulphonyl)-1H-cyclopentapyridazine-3-carboxylate 

Relevant academic research and scientific papers

1,4,5,6-Tetrahydropyridazines by Cycloaddition of Enol Ethers to Azoalkenes and their Aromatisation to Pyridazines.

Transient azoalkenes generated from acyl- and 4-tolylsulphonyl-hydrazones of α-haloacetophenones and of ethyl bromopyruvate are intercepted by cycloaddition to enol ethers, giving 6-alkoxy-1,4,5,6-tetrahydropyridazines (2). 6-Alkoxy-3-aryl-1,4,5,6-tetrahydropyridazines are converted by reaction with sodium ethoxide into 3-arylpyridazines (3).