1006881-86-2Relevant academic research and scientific papers
Titanium(III)-induced intramolecular radical cyclization of epoxyallene ethers: an efficient method for synthesis of multifunctional tetrahydrofurans
Xu, Lubin,Huang, Xian
, p. 500 - 503 (2008)
Ti(III)-mediated intramolecular free radical cyclization of epoxyallene ethers in an exo-mode was studied. The reaction afforded an efficient and highly regioselective method of synthetically important 3-vinyl-4-hydroxymethyl tetrahydrofurans.
Dual amine and palladium catalysis in diastereo- and enantioselective allene carbocyclization reactions
Li, Meiling,Datta, Swarup,Barber, David M.,Dixon, Darren J.
supporting information, p. 6350 - 6353 (2013/02/23)
A pyrrolidine and Pd catalyzed diastereoselective carbocyclization of aldehyde and ketone-linked allenes has been developed. The cooperative organo/metal-catalyzed cyclization reaction, which presumably proceeds via an enamine intermediate, is efficient and broad in scope. Also, it has been extended to a catalytic asymmetric variant using diarylprolinol-based organocatalysts to afford substituted cyclopentane and pyrrolidine reaction products in up to 82% ee.
Organocatalyzed cyclizations of π-allylpalladium complexes: A new method for the construction of five- and six-membered rings
Bihelovic, Filip,Matovic, Radomir,Vulovic, Bojan,Saicic, Radomir N.
, p. 5063 - 5066 (2008/03/28)
Synergic combination of organotransition metal catalysis and organocatalysis allows, for the first time, the Tsuji-Trost cyclization of aldehydes. A catalytic asymmetric variant of the reaction is also possible.
