1006901-27-4Relevant academic research and scientific papers
Diastereoselective Pomeranz-Fritsch-Bobbitt synthesis of (S)-(-)-O-methylbharatamine using (S)-N-tert-butanesulfinimine as a substrate
Grajewska, Agnieszka,Rozwadowska, Maria D.
, p. 2910 - 2914 (2008/09/16)
The protoberberine-type alkaloid, (S)-(-)-O-methylbharatamine, has been synthesized in six steps involving the addition of laterally lithiated o-toluamide to (S)-N-tert-butanesulfinimine as the crucial process. The target alkaloid was obtained in 24.4% overall yield with 88% ee.
