1007105-58-9Relevant academic research and scientific papers
Stereoelectronic structure of α-bromoalkenyl trifluoromethyl ketones
Chipanina,Aksamentova,Rulev, A. Yu.
, p. 1431 - 1436 (2009)
The results of quantum-chemical calculations at the B3LYP/6-311G level of theory showed that (Z)-α-bromo-β-arylalkenyl trifluoromethyl ketones are more stable than the corresponding E isomers by 4-5 kcal/mol. Relatively large positive charge on the olefin
Domino transformations of gem-trifluoroacetyl(bromo)alkenes under the action of secondary amines
Rulev, Alexander Yu.,Uchakov, Igor A.,Nenajdenko, Valentin G.,Balenkova, Elisabeth S.,Voronkov, Mikhail G.
, p. 6039 - 6045 (2008/09/17)
2-Bromo-3-arylpropenyl trifluoromethyl ketones underwent aza-Michael/hydroxyalkylation domino reactions triggered by secondary amines to give unexpectedly 2-amino-1-trifluoromethyl indenols in good yields. The process was found to involve the intermediate
