1007112-35-7

Basic information

• Product Name: 4-BENZOXAZOLECARBOXYLIC ACID, 2-CHLORO, METHYL ESTER
• Synonyms: 4-BENZOXAZOLECARBOXYLIC ACID, 2-CHLORO, METHYL ESTER;Methyl 2-chlorobenzo[d]oxazole-4-carboxylate;Methyl 2-chloro-1,3-benzoxazole-4-carboxylate;CAS:1007112-35-7
• CAS NO: 1007112-35-7
• Molecular Formula: C₉H₆ClNO₃
• Molecular Weight: 212
• Mol File: 1007112-35-7.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 4-BENZOXAZOLECARBOXYLIC ACID, 2-CHLORO, METHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 4-BENZOXAZOLECARBOXYLIC ACID, 2-CHLORO, METHYL ESTER(1007112-35-7)
• EPA Substance Registry System: 4-BENZOXAZOLECARBOXYLIC ACID, 2-CHLORO, METHYL ESTER(1007112-35-7)

Safety Data

• Hazardous Substances Data: 1007112-35-7(Hazardous Substances Data)

Usage

General Description

The chemical "4-Benzoxazolecarboxylic Acid, 2-Chloro, Methyl Ester" is a specialized scientific compound with a name derived from its structural components. The compound includes elements of benzoxazole, carboxylic acid, and methyl ester, all of which are crucial in chemical reactions. Benzoxazole is a heterocyclic compound, carboxylic acid is an organic acid containing carboxyl functional group, while methyl ester refers to an ester with a methyl group. The 2-chloro refers to the presence of chlorine in the second position of the molecular structure. This chemical can be used in various scientific and industrial applications, though its specific properties and uses can vary.

Upstream product

• 213685-54-2 methyl 2-thioxo-2,3-dihydrobenzoxazole-4-carboxylate 

Downstream Products

• 1007113-35-0 (S)-methyl 2-(4-benzyl-2-ethylpiperazine-1-yl)benzoxazole-4-carboxylate 
• 1007112-69-7 methyl 2-((3S,5S)-3,5-dimethylmorpholino)benzoxazole-4-carboxylate 
• 100246-04-6 methyl 2-oxo-2,3-dihydro-1,3-benzoxazole-4-carboxylate 
• 1007112-70-0 (S)-methyl 2-(4-benzyl-2-isopropylpiperazin-1-yl)benzoxazole-4-carboxylate 

Relevant articles and documents

Discovery of 2-substituted benzoxazole carboxamides as 5-HT3 receptor antagonists

A new class of 2-substituted benzoxazole carboxamides are presented as potent functional 5-HT3 receptor antagonists. The chemical series possesses nanomolar in vitro activity against human 5-HT3A receptors. A chemistry optimization program was conducted and identified 2-aminobenzoxazoles as orally active 5-HT3 receptor antagonists with good metabolic stability. These novel analogues possess drug-like characteristics and have potential utility for the treatment of diseases attributable to improper 5-HT3 receptor function, especially diarrhea predominant irritable bowel syndrome (IBS-D).

BENZOOXAZOLE, OXAZOLOPYRIDINE, BENZOTHIAZOLE AND THIAZOLOPYRIDINE DERIVATIVES

This invention is concerned with compounds of the formula (I) wherein X, A, B, R1, R2 and G are as defined in the description and claims, and pharmaceutically acceptable salts thereof. The invention further relates to pharmaceutical