1007121-63-2Relevant academic research and scientific papers
Palladium-catalyzed intramolecular chloroamination of alkenes
Michael, Forrest E.,Sibbald, Paul A.,Cochran, Brian M.
supporting information; experimental part, p. 793 - 796 (2009/04/06)
A mild and facile Pd-catalyzed intramolecular chloroamination of unactivated alkenes has been described. This reaction takes place at room temperature and is tolerant of synthetically useful acid-sensitive functional groups. Generally high exo-selectiviti
Synthesis of 2,6-disubstituted piperazines by a diastereoselective palladium-catalyzed hydroamination reaction
Cochran, Brian M.,Michael, Forrest E.
, p. 329 - 332 (2008/09/19)
(Chemical Equation Presented) A highly diastereoselective intramolecular hydroamination is the key step in a modular synthesis of 2,6-disubstituted piperazines. The requisite hydroamination substrates were prepared in excellent yields by nucleophilic disp
