100717-12-2Relevant academic research and scientific papers
Radioiodinated benzyloxybenzene derivatives: A class of flexible ligands target to β-amyloid plaques in Alzheimer's brains
Yang, Yanping,Cui, Mengchao,Zhang, Xiaoyang,Dai, Jiapei,Zhang, Zhiyong,Lin, Chunping,Guo, Yuzhi,Liu, Boli
, p. 6030 - 6042 (2014)
Benzyloxybenzene, as a novel flexible scaffold without rigid planarity, was synthesized and evaluated as ligand toward Aβ plaques. The binding site calculated for these flexible ligands was the hydrophobic Val18-Phe20 channel on the flat surface of Aβ fib
