Welcome to LookChem.com Sign In|Join Free

CAS

  • or

1007206-24-7

4-(4-chloro-7-(pyridin-3-yl)-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-2-yl)morpholine is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

1007206-24-7 Suppliers

Post Buying Request

Recommended suppliersmore

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier
  • 1007206-24-7 Structure

  • Basic information

    1. Product Name: 4-(4-chloro-7-(pyridin-3-yl)-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-2-yl)morpholine
    2. Synonyms: 4-(4-chloro-7-(pyridin-3-yl)-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-2-yl)morpholine
    3. CAS NO:1007206-24-7
    4. Molecular Formula:
    5. Molecular Weight: 317.778
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1007206-24-7.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 4-(4-chloro-7-(pyridin-3-yl)-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-2-yl)morpholine(CAS DataBase Reference)
    10. NIST Chemistry Reference: 4-(4-chloro-7-(pyridin-3-yl)-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-2-yl)morpholine(1007206-24-7)
    11. EPA Substance Registry System: 4-(4-chloro-7-(pyridin-3-yl)-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-2-yl)morpholine(1007206-24-7)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1007206-24-7(Hazardous Substances Data)

1007206-24-7 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1007206-24-7 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,0,7,2,0 and 6 respectively; the second part has 2 digits, 2 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 1007206-24:
(9*1)+(8*0)+(7*0)+(6*7)+(5*2)+(4*0)+(3*6)+(2*2)+(1*4)=87
87 % 10 = 7
So 1007206-24-7 is a valid CAS Registry Number.

1007206-24-7Relevant articles and documents

Discovery and biological activity of a novel class i PI3K inhibitor, CH5132799

Ohwada, Jun,Ebiike, Hirosato,Kawada, Hatsuo,Tsukazaki, Masao,Nakamura, Mitsuaki,Miyazaki, Takuya,Morikami, Kenji,Yoshinari, Kiyoshi,Yoshida, Miyuki,Kondoh, Osamu,Kuramoto, Shino,Ogawa, Kotaro,Aoki, Yuko,Shimma, Nobuo

, p. 1767 - 1772 (2011)

Phosphatidylinositol 3-kinase (PI3K) is a lipid kinase and a promising therapeutic target for cancer. Using structure-based drug design (SBDD), we have identified novel PI3K inhibitors with a dihydropyrrolopyrimidine skeleton. Metabolic stability of the first lead series was drastically improved by replacing phenol with aminopyrimidine moiety. CH5132799, a novel class I PI3K inhibitor, exhibited a strong inhibitory activity especially against PI3Kα (IC50 = 0.014 μM). In human tumor cell lines with PI3K pathway activation, CH5132799 showed potent antiproliferative activity. CH5132799 is orally available and showed significant antitumor activity in PI3K pathway-activated human cancer xenograft models in mice.

BICYCLIC HETEROARENES AND METHODS OF THEIR USE

-

Page/Page column 60, (2021/12/30)

Disclosed are compounds useful in the treatment of neurological disorders. The compounds described herein, alone or in combination with other pharmaceutically active agents, can be used for treating or preventing neurological diseases.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 1007206-24-7