1007224-79-4

Upstream product

• 10605-43-3 1,1-bis(p-bromophenyl)ethylene 
• 86988-52-5 1,1-bis(4-bromophenyl)ethanol 
• 1122-91-4 4-bromo-benzaldehyde 

Downstream Products

• 138534-92-6 Toluene-4-sulfonic acid 2,2-bis-(4-bromo-phenyl)-ethyl ester 

Relevant academic research and scientific papers

Selective One-Pot Three-Step Cascade Reaction: From Aromatic Aldehydes to 2,2-Diphenylethanol Derivatives

We report herein a green and scalable one-pot, three-step, pinacol-coupling-rearrangement-reduction cascade reaction useful for the formation of 2,2-diphenylethanol derivatives. The reaction is carried out in water in the presence of a commercially available and regenerable supported acid under moderate pressure. A dozen of aromatic aldehydes have been successfully submitted to the standard protocol giving the target 2,2-diarylethanol derivatives in good yield (70-85%).

Substituent Effect Studies of Aryl-Assisted Solvolyses. I. The Acetolysis of 2,2-Bis(substituted phenyl)ethyl p-Toluenesulfonates

The substituent effect on the acetolysis of 2,2-bis(substituted phenyl)ethyl p-toluenesulfonates at 90.10 deg C can be described accurately in terms of the Yukawa-Tsuno (LArSR) relationship, giving a ρ value of -4.44 and an r value of 0.53. The substituent effect correlation of this system carrying two aryls is quite comparable to that of the 2-methyl-2-phenylpropyl system carrying a single aryl group, suggesting the close similarity in the structure of the transition states between the systems. The results can be reasonably accounted for on the basis of the accepted mechanism of this reaction, involving a rate-determining aryl-assisted transition state where only one aryl group of the two β-aryl groups participates.