1007362-84-6Relevant academic research and scientific papers
New functional derivatives of 9-phenylquinine
Boratynski, Przemyslaw J.,Skarzewski, Jacek
experimental part, p. 3113 - 3119 (2009/12/28)
A rapid synthesis of various 9-aryl derivatives of quinine is presented. They are obtained via coupling reactions of functionalized arylmagnesium halides and 9-chloroquinine.
Stereoselective C9 arylation and vinylation of Cinchona alkaloids
Boratynski, Przemystaw J.,Turowska-Tyrk, Ilona,Skarzewski, Jacek
, p. 385 - 388 (2008/09/20)
A simple and efficient method for the highly stereoselective C-9 arylation and vinylation of Cinchona alkaloids was developed. Both 9S- and 9R-chloroquinine with PhMgBr yielded 9S-phenylquinine (X-ray structure). The reactions with various aryl and vinyl
