1007362-95-9

Upstream product

• 796113-35-4 1,1-dimethylethyl 4-(2,2-dimethyl-4,6-dioxo-1,3-dioxan-5-ylidene)-1-piperidinecarboxylate 
• 89794-02-5 4-bromo-2-chlorotoluene 
• 1007362-94-8 C₂₃H₃₀ClNO₆ 

Downstream Products

• 1007363-02-1 C₅H₅N*C₁₉H₂₆ClNO₄ 

Relevant academic research and scientific papers

Synthesis of a tertiary carbinamide via a novel Rh-catalyzed asymmetric hydrogenation

(Chemical Equation Presented) Asymmetric hydrogenation of allylic dimethylcarbinamide 2 with 1 mol % of cationic Rh(I)-Josiphos complex in THF under 500 psi of H2 generated the corresponding tertiary carbinamide 1 in 98.5% assay yield and a 94:

ACYLATED SPIROPIPERIDINE DERIVATIVES AS MELANOCORTIN-4 RECEPTOR MODULATORS

Certain novel N-acylated spiropiperidine derivatives are ligands of the human melanocortin receptor(s) and, in particular, are selective ligands of the human melanocortin-4 receptor (MC-4R). They are therefore useful for the treatment, control, or prevention of diseases and disorders responsive to the modulation of MC-4R, such as obesity, diabetes, nicotine addiction, alcoholism, sexual dysfunction, including erectile dysfunction and female sexual dysfunction.