1007389-58-3Relevant academic research and scientific papers
Synthesis and crystal structure of thiazole orange derivative
Fei, Xuening,Gu, Yingchun,Lan, Yunquan,Shi, Bin,Zhang, Baolian
experimental part, p. 1232 - 1236 (2012/07/13)
The title compound of Thiazole Orange derivative was synthesized by the reaction of benzothiazolium and 4-methyl quinoline salts, which was determined by 1HNMR and MS. A crystalline hydrate of thiazole orange derivative was obtained when the crystal formed and characterized by single-crystal X-ray diffraction. The crystal belongs to the Triclinic system, and the cell parameters of space group P-1 were a = 10.162(2) A, b = 10.501(2) A, c = 11.040(2) A, α = 92.17(3)o, β = 117.10(3) o, γ = 92.28(3)o, V = 1045.9(4) A3, Z = 2, Dc = 1.380 mg/m-3, μ = 0.2 mm-1, F(000) = 460, and the final R = 0.0625 and wR = 0.1862 for 3658 observed reflections (I > 2σ(I)). The two aromatic rings linked by the methylene bridged chain are a coplanar structure.
Targeted thiazole orange derivative with folate: Synthesis, fluorescence and in vivo fluorescence imaging
Fei, Xuening,Gu, Yingchun,Wang, Yiqi,Meng, Qingyang,Zhang, Baolian
scheme or table, p. 6983 - 6992 (2011/02/25)
A Thiazole Orange conjugated with folate derivative was synthesized in two steps. Firstly, folate was coupled with 1-(3-aminopropyl)-4-methylquinolinium bromide to afford folate-methylquinolinium bromide, which then reacted with benzothiazolium to obtain
Thiazole Orange derivatives: Synthesis, fluorescence properties, and labeling cancer cells
Fei, Xuening,Gu, Yingchun,Ban, Ying,Liu, Zhijun,Zhang, Baolian
experimental part, p. 585 - 591 (2009/07/04)
A series of Thiazole Orange (TO) derivatives were synthesized and modified by introducing different substitutional groups on benzothiazole and 4-methylquinoline All the TO derivatives were confirmed by 1HNMR and MS. TO derivative bearing NHsub
