1007391-35-6Relevant academic research and scientific papers
The diastereoselective synthesis of difluoro-βlactam using Reformatsky-Honda reaction
Tarui, Atsushi,Kondo, Keigo,Taira, Hiroko,Sato, Kazuyuki,Omote, Masaaki,Kumadaki, Itsumaro,Ando, Akira
experimental part, p. 203 - 208 (2009/09/06)
The high diastereoselective synthesis of chiral difluoro-β-lactams (3) was attained by treatment of ethyl bromodifluoroacetate (1), 2-hydroxy-l-phenylethyl group substituted imines (2) and diethylzinc in the presence of rhodium-catalyst. The absolute conf
