1007392-73-5Relevant academic research and scientific papers
Design and optimization of new piperidines as renin inhibitors
Corminboeuf, Olivier,Bezenon, Olivier,Grisostomi, Corinna,Remeň, ?ubo?,Richard-Bildstein, Sylvia,Bur, Daniel,Prade, Lars,Hess, Patrick,Strickner, Panja,Fischli, Walter,Steiner, Beat,Treiber, Alexander
scheme or table, p. 6286 - 6290 (2010/11/18)
The discovery of a new series of piperidine-based renin inhibitors is described herein. SAR optimization upon the P3 renin sub-pocket is described, leading to the discovery of 9 and 41, two bioavailable renin inhibitors orally active at low doses in a tra
Novel Piperidine Carboxylic Acid Amide Derivatives
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Page/Page column 26, (2008/12/08)
The invention relates to novel piperidine carboxylic acid amide derivatives and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of these
