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1H-Isoindol-1-one, 5-fluoro-2,3-dihydro-6-hydroxy-, also known as TAK-438, is a chemical compound with potential as a gastric proton pump inhibitor. It is characterized by its unique structure and properties that enable it to target the proton pump in the stomach, thereby inhibiting gastric acid secretion. This makes TAK-438 a promising candidate for the development of new and effective treatments for acid-related disorders, such as gastroesophageal reflux disease and peptic ulcers.

1007455-25-5

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1007455-25-5 Usage

Uses

Used in Pharmaceutical Industry:
1H-Isoindol-1-one, 5-fluoro-2,3-dihydro-6-hydroxyis used as a gastric proton pump inhibitor for its ability to reduce gastric acid secretion. This application is particularly relevant for treating disorders such as gastroesophageal reflux disease and peptic ulcers, where the inhibition of gastric acid can provide relief from related symptoms.
1H-Isoindol-1-one, 5-fluoro-2,3-dihydro-6-hydroxy-'s unique structure and properties make it a valuable asset in the development of new treatments for acid-related disorders, potentially offering more effective and targeted therapies for patients suffering from these conditions.

Check Digit Verification of cas no

The CAS Registry Mumber 1007455-25-5 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,0,7,4,5 and 5 respectively; the second part has 2 digits, 2 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1007455-25:
(9*1)+(8*0)+(7*0)+(6*7)+(5*4)+(4*5)+(3*5)+(2*2)+(1*5)=115
115 % 10 = 5
So 1007455-25-5 is a valid CAS Registry Number.
InChI:InChI=1S/C8H6FNO2/c9-6-1-4-3-10-8(12)5(4)2-7(6)11/h1-2,11H,3H2,(H,10,12)

1007455-25-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 5-fluoro-6-hydroxy-2,3-dihydroisoindol-1-one

1.2 Other means of identification

Product number -
Other names 5-fluoro-6-hydroxy-2,3-dihydro-isoindol-1-one

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1007455-25-5 SDS

1007455-25-5Downstream Products

1007455-25-5Relevant academic research and scientific papers

Synthesis of methyl-, fluoro-, and chloro-substituted 6-hydroxyisoindolin-1-ones

Powers, James J.,Favor, David A.,Rankin, Trent,Sharma, Rashmi,Pandit, Chetan,Jeganathan, Azhwarsamy,Maiti, Samarendra N.

supporting information; experimental part, p. 1267 - 1269 (2009/09/05)

The synthesis of a series of methyl-, fluoro-, and chloro-substituted 6-hydroxyisoindolin-1-ones is described.

ISOINDOLE DERIVATIVES

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Page/Page column 29; 30, (2010/11/30)

This invention relates to compounds of formula (I) or pharmaceutically acceptable salts thereof, a process of making these compounds, pharmaceutical compositions containing one or more of these compounds or their salts, and their use for the treatment of schizophrenia, bipolar disorder, or other central nervous system disorders.

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