1007570-83-3Relevant articles and documents
Design of annulated pyrazoles as inhibitors of HIV-1 reverse transcriptase
Sweeney, Zachary K.,Harris, Seth F.,Arora, Nidhi,Javanbakht, Hassan,Li, Yu,Fretland, Jennifer,Davidson, James P.,Billedeau, J. Roland,Gleason, Shelley K.,Hirschfeld, Donald,Kennedy-Smith, Joshua J.,Mirzadegan, Taraneh,Roetz, Ralf,Smith, Mark,Sperry, Sarah,Suh, Judy M.,Wu, Jeffrey,Tsing, Stan,Villase?or, Armando G.,Paul, Amber,Su, Guoping,Heilek, Gabrielle,Hang, Julie Q.,Zhou, Amy S.,Jernelius, Jesper A.,Zang, Fang-Jie,Klumpp, Klaus
experimental part, p. 7449 - 7458 (2010/01/21)
Non-nucleoside reverse transcriptase inhibitors (NNRTIs) are recommended components of preferred combination antiretroviral therapies used for the treatment of HIV. These regimens are extremely effective in suppressing virus replication. Structure-based o