1007587-59-8Relevant articles and documents
Click-connected ligand scaffolds: macrocyclic chelates for asymmetric hydrogenation
Qing, Zhang,Takacs, James M.
, p. 545 - 548 (2008/09/17)
Click chemistry is used to construct ligand scaffolds for a series of chiral diphosphites. Enantioselectivity as high as 97% ee is obtained using these click ligands in rhodium-catalyzed asymmetric hydrogenation. Control experiments and spectroscopic data suggest that a 16-membered P,P-macrocyclic Rh(1) chelate is formed.