100776-48-5

Upstream product

• 100741-03-5 (2S,3S)-3-((R)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-2-formylamino-3-hydroxy-propionic acid methyl ester 
• 100741-07-9 (2S,3S,4R)-3,4,5-trihydroxy-2-amino pentanoic acid 
• 501-53-1 benzyl chloroformate 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 81366-43-0 (3S,4S,5R)-(4-hydroxy-5-hydroxymethyl-2-oxotetrahydrofuran-3-yl)carbamic acid benzyl ester 

Downstream Products

• 620960-66-9 (S)-2-[(2S,3S,4R)-5-Azido-2-[(S)-2-tert-butoxycarbonylamino-3-(4-hydroxy-3,5-diiodo-phenyl)-propionylamino]-3,4-bis-(tert-butyl-dimethyl-silanyloxy)-pentanoylamino]-3-(3,5-dibromo-4-hydroxy-phenyl)-propionic acid methyl ester 
• 620960-65-8 (S)-2-[(2S,3S,4R)-5-Azido-2-tert-butoxycarbonylamino-3,4-bis-(tert-butyl-dimethyl-silanyloxy)-pentanoylamino]-3-(3,5-dibromo-4-hydroxy-phenyl)-propionic acid methyl ester 
• 620960-81-8 2-(N-benzyloxycarbonyl)amino-2-deoxy-3,4,5-tri(tert-butyldimethylsilyloxy)-1-pivaloyl-D-arabinitol 
• 620960-80-7 2,2-Dimethyl-propionic acid (2R,3S,4R)-2-benzyloxycarbonylamino-3,5-bis-(tert-butyl-dimethyl-silanyloxy)-4-hydroxy-pentyl ester 
• 620960-79-4 [(1R,2S,3R)-2,4-Bis-(tert-butyl-dimethyl-silanyloxy)-3-hydroxy-1-hydroxymethyl-butyl]-carbamic acid benzyl ester 

Relevant academic research and scientific papers

Stereoselective Synthesis of 2-Amino-2-deoxy-D-arabinose and 2-Deoxy-D-ribose

An efficient method for the stereoselective synthesis of 2-amino-2-deoxy-D-arabinose and 2-deoxy-D-ribose is described.The key step in this method was accomplished by the nucleophilic addition of methyl isocyanoacetate to 2,3-O-isopropylidene-D-glyceraldehyde with high erythro-selectivity (nearly 100percent).Subsequent intermolecular cyclization predominantly gave the desired oxazoline derivative (trans-form), in which two new chiral centers were formed.The oxazoline derivative was efficiently converted to both 2-amino-2-deoxy-D-arabinose and 2-deoxy-D-ribose.