10078-25-8 Usage
Uses
Perphenazine Sulfoxide (Perphenazine EP Impurity A) acts as a D2 dopamine receptor antagonist; α-adrenergic receptor antagonist and σ-receptor agonist; phenothiazine antipsychotic. Inhibits glutamate dehydrogenase in vitro. Antipsychotic.
Check Digit Verification of cas no
The CAS Registry Mumber 10078-25-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,0,0,7 and 8 respectively; the second part has 2 digits, 2 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 10078-25:
(7*1)+(6*0)+(5*0)+(4*7)+(3*8)+(2*2)+(1*5)=68
68 % 10 = 8
So 10078-25-8 is a valid CAS Registry Number.
InChI:InChI=1/C21H26ClN3O2S/c22-17-6-7-21-19(16-17)25(18-4-1-2-5-20(18)28(21)27)9-3-8-23-10-12-24(13-11-23)14-15-26/h1-2,4-7,16,26H,3,8-15H2
10078-25-8Relevant articles and documents
Convenient oxidation of phenothiazine salts to their sulfoxides with aqueous nitrous acid
Owens,Juenge,Poklis
, p. 334 - 336 (1989)
A simple method is reported for the preparation of gram quantities of phenothiazine sulfoxides by aqueous nitrous acid oxidation of phenothiazines at room temperature. The chiral levomepromazine gave rise to diastereoisomeric products analogous to those reported for thioridazine sulfoxidation.
Studies on phenothiazines. 2. Synthesis of a 10 N--substituted phenothiazine sulfoxide and its spectroscopic characterization
Kreyenbuehl,Joshi,Perlia
, p. 248 - 252 (2007/10/04)
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