1007839-76-0Relevant articles and documents
Highly enantioselective direct syn- and anti-aldol reactions of dihydroxyacetones catalyzed by chiral primary amine catalysts
Luo, Sanzhong,Xu, Hui,Zhang, Long,Li, Jiuyuan,Cheng, Jin-Pei
, p. 653 - 656 (2008)
We present herein simple primary-tertiary diamine-Bronsted acid conjugates that catalyze both syn- and anti-aldol reactions of dihydroxyacetones (DHAs) with high diastereoselectivities and enantioselectivities. This type of organocatalysts functionally mimics all four DHA aldolases, namely L-fuculose-1-phosphate aldolase, D-tagatose-1,6-diphosphate aldolase, D-fructose-1,6-diphosphate aldolase, and L-rhamnulose-1-phosphate aldolase.