100784-47-2Relevant articles and documents
Synhesis of Heterocyclic Compounds. Part 46. The reactions of Malonamide and 2-Cyanoacetamide with Substituted Propenones
Soto, Jose L.,Seoane, Carlos,Zamorano, Pilar,Rubio, Maria J.,Monforte, Alejandro,Quinteiro, Margarita
, p. 1681 - 1686 (2007/10/02)
The synthesis of substituted 2-pyridone derivatives from malonamide (1) and 2-cyanoacetamide (2) is reported.Conjugate addition of these compounds to substituted propenones (3) and (4) leads to 6-hydroxy-2-piperidones, which can be dehydrated and aromatiz