100784-48-3

Upstream product

• 75238-80-1 3,4-dicyano-6-hydroxy-4,6-diphenyl-piperidin-2-one 
• 75617-37-7 3,5-dicyano-4,6-diphenyl-3,4-dihydropyridin-2(1H)-one 
• 20413-05-2 (E)-2-Benzoyl-3-phenyl-acrylonitrile 
• 75238-88-9 3-carbamoyl-5-cyano-6-hydroxy-4,6-diphenylpiperidin-2-one 
• 75238-89-0 3-carbamoyl-5-cyano-4,6-diphenyl-3,4-dihydropyridin-2-(1H)-one 

Downstream Products

• 100784-53-0 6-oxo-2,4-diphenyl-1,6-dihydropyridine-3-carbonitrile 

Relevant academic research and scientific papers

Synhesis of Heterocyclic Compounds. Part 46. The reactions of Malonamide and 2-Cyanoacetamide with Substituted Propenones

The synthesis of substituted 2-pyridone derivatives from malonamide (1) and 2-cyanoacetamide (2) is reported.Conjugate addition of these compounds to substituted propenones (3) and (4) leads to 6-hydroxy-2-piperidones, which can be dehydrated and aromatiz