100795-75-3

Upstream product

• 90-02-8 salicylaldehyde 
• 57-13-6 urea 
• 123-54-6 acetylacetone 
• 17356-08-0 thiourea 

Downstream Products

• 1254120-85-8 C₂₀H₁₈N₂O₄ 

Relevant academic research and scientific papers

Coumarin-chalcone hybrids targeting insulin receptor: Design, synthesis, anti-diabetic activity, and molecular docking

Four series of thirteen new coumarin-chalcone hybrids (DPCU 1–13, DPCT 1–13, DCCU 1–13 and DCCT 1–13) were designed and synthesized using Biginelli synthesis, Pechmann condensation, Acetylation, and Claisen-Schmidt reactions. Synthesized compounds were te

Exploiting silver trifluoromethanesulfonate as efficient and reusable catalyst for the synthesis of dihydropyrimidine derivatives under different reaction environments

Different results were generated under different reaction conditions for the multicomponent reactions. Herein, an efficiently improved and mild protocol for the synthesis of dihydropyrimidine derivatives using cheap silver trifluoromethanesulfonate (CFsu

Dihydropyrimidones: A ligands urease recognition study and mechanistic insight through in vitro and in silico approach

Scaffold varied dihydropyrimidone derivatives 1–20 were evaluated for their selective urease inhibitory kinetics potential. Compounds 1, 2, 3, 4, 5, 6, and 12 were found to be the most promising urease inhibitors and showed the inhibition (Ki v

Fe3O4@Silica sulfuric acid core-shell composite as a novel nanomagnetic solid acid: Synthesis, characterization and application as an efficient and reusable catalyst for one-pot synthesis of 3,4-dihydropyrimidinones/thiones under sol

Abstract A simple and convenient method was used to prepare Fe3O4@Silica sulfuric acid core-shell composite using Fe3O4 spheres as the core and silica sulfuric acid nanoparticles as the shell. Magnetite nanopart

One-pot Synthesis of 3,4-Dihydropyrimidin-2(1H)-ones Catalysed by Cupric Acetate under Solvent-free Conditions

A solvent-free synthesis of 3,4-dihydropyrimidin-2(1H)-ones from aromatic aldehydes, β-keto ester/acetyl acetone and urea catalysed by cupric acetate under thermal condition is reported as a simple and an efficient protocol. Compared with classical Bigine

Sustainable synthetic approaches using [C16Im][Oxa] as a flexible organocatalyst and DFT studies toward 3,4-dihydropyrimidinones and benzoxazines

Abstract: Easily accessible 1-hexadecyl-1H-imidazol-3-ium oxalate is highly efficient Br?nsted type acidic catalyst for the selected multicomponent one-pot reactions. The short reaction times, easy workup procedures, and green metal-free conditions for th

Synthesis and characterization of nano acid catalyst derived from rice husk silica and its application for the synthesis of 3,4-dihydropyrimidinones/thiones compounds

In the present work, the extraction of silica nanoparticles from the rice husk followed by the modification using an acidic ionic liquid containing imidazolium butyl sulfonic acid through a sol-gel method (RH@[SiPrImBuSO3H]Cl) has been investig

Air-stable zirconocene bis(perfluorobutanesulfonate) as a highly efficient catalyst for synthesis of N-heterocyclic compounds

Zirconocene bis(perfluorobutanesulfonate) is air- and water-stable and proved to be ionic on basis of conductivity measurements. It exhibits high catalytic efficiency for the synthesis of N-heterocyclic compounds under solvent-free condition, such as benzimidazoles, benzodiazepines, dihydropyrimidinones and dihydropyridines under mild condition. Furthermore, it can be reused without loss of activity in a test of five cycles. This catalytic system affords a simple and efficient approach for the synthesis of N-heterocyclic compounds.

Ultrasound-mediated synthesis of 3,4-dihydropyrimidin-2-(1H)-ones (or Thiones) with NaHSO4·H 2O

A fast and efficient Biginelli synthesis of 3,4-dihydropyrimidin-2-(1H)- ones (or thiones) by the reaction of aromatic aldehydes, β-dicarbonyls, and urea/thiourea using NaHSO4·H2O/ultrasound system is presented. The reactions were ca

BiVO4-NPs: an efficient nano-catalyst for the synthesis of biscoumarins, bis(indolyl)methanes and 3,4-dihydropyrimidin-2(1H)-ones (thiones) derivatives

BiVO4-NPs can be used as an efficient and reusable nano-catalyst for the promotion of the synthesis of biscoumarins, bis(indolyl)methanes and 3,4-dihydropyrimidin-2(1H)-ones (thiones) derivatives. The structures of the products were characteriz