1008119-83-2

Basic information

• Product Name: 3,4-diMethoxy-N-(4-(3-nitrophenyl)-5-(piperidin-1-ylMethyl)thiazol-2-yl)benzenesulfonaMide
• Synonyms: 3,4-diMethoxy-N-(4-(3-nitrophenyl)-5-(piperidin-1-ylMethyl)thiazol-2-yl)benzenesulfonaMide;JM 6;3,4-Dimethoxy-N-[4-(3-nitrophenyl)-5-(1-piperidinylmethyl)-2-thiazolyl]-benzenesulfonamide;2-(3,4-Dimethoxybenzenesulfonylamino)-4-(3-nitrophenyl)-5-(piperidin-1-yl)methylthiazole;JM 6 (enzyme inhibitor)
• CAS NO: 1008119-83-2
• Molecular Formula: C23H26N4O6S2
• Molecular Weight: 518.60574
• EINECS: -0
• Mol File: 1008119-83-2.mol
• Article Data: 1

Chemical Properties

• Appearance: white to beige/
• Storage Temp.: 2-8°C
• Solubility: DMSO: soluble2mg/mL (clear solution, warmed)
• CAS DataBase Reference: 3,4-diMethoxy-N-(4-(3-nitrophenyl)-5-(piperidin-1-ylMethyl)thiazol-2-yl)benzenesulfonaMide(CAS DataBase Reference)
• NIST Chemistry Reference: 3,4-diMethoxy-N-(4-(3-nitrophenyl)-5-(piperidin-1-ylMethyl)thiazol-2-yl)benzenesulfonaMide(1008119-83-2)
• EPA Substance Registry System: 3,4-diMethoxy-N-(4-(3-nitrophenyl)-5-(piperidin-1-ylMethyl)thiazol-2-yl)benzenesulfonaMide(1008119-83-2)

Safety Data

• Hazard Codes: T
• Statements: 25
• Safety Statements: 45
• WGK Germany: 3
• Hazardous Substances Data: 1008119-83-2(Hazardous Substances Data)

Usage

Uses

Different sources of media describe the Uses of 1008119-83-2 differently. You can refer to the following data:
1. 3,4-dimethoxy-N-[4-(3-nitrophenyl)-5-(1-piperidinylmethyl)-2-thiazolyl]-benzenesulfonamide is also known as JM6. Studies have shown JM6 participates in the inhibitory effects towards kynurenine 3-mono oxygenase in its activities in blood ameliorates neurodegeneration.
2. 3,4-dimethoxy-N-[4-(3-nitrophenyl)-5-(1-piperidinylmethyl)-2-thiazolyl]-benzenesulfonamide is also known as JM6. Studies have shown JM6 participates in the inhibitory effects towards kynurenine 3-monooxygenase in its activities in blood ameliorates neurodegeneration.

Upstream product

• 110-89-4 piperidine 

Relevant articles and documents

SMALL MOLECULE INHIBITORS OF KYNURENINE-3-MONOOXYGENASE

The present invention relates to compounds of formula (Ia) or (Ib) and their tautomers and/or pharmaceutically acceptable salts and compositions and methods of uses thereof.