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3,4-Dimethoxy-n-(4-(3-nitrophenyl)-5-(piperidin-1-ylmethyl)thiazol-2-yl)benzenesulfonamide, also known as JM6, is a complex organic compound with a unique chemical structure. It is characterized by the presence of a benzene ring with two methoxy groups at the 3rd and 4th positions, a sulfonamide group, and a thiazol-2-yl group connected to a piperidin-1-ylmethyl moiety and a 3-nitrophenyl group. 3,4-Dimethoxy-n-(4-(3-nitrophenyl)-5-(piperidin-1-ylmethyl)thiazol-2-yl)benzenesulfonamide has been studied for its potential therapeutic applications.

1008119-83-2

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1008119-83-2 Usage

Uses

Used in Pharmaceutical Industry:
3,4-Dimethoxy-n-(4-(3-nitrophenyl)-5-(piperidin-1-ylmethyl)thiazol-2-yl)benzenesulfonamide, or JM6, is used as a potential therapeutic agent for neurodegenerative diseases. It has been shown to inhibit the activity of kynurenine 3-monooxygenase in the blood, which is involved in the production of neurotoxic metabolites. By reducing the activity of this enzyme, JM6 may help ameliorate neurodegeneration and protect against the progression of neurodegenerative disorders.

Check Digit Verification of cas no

The CAS Registry Mumber 1008119-83-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,0,8,1,1 and 9 respectively; the second part has 2 digits, 8 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1008119-83:
(9*1)+(8*0)+(7*0)+(6*8)+(5*1)+(4*1)+(3*9)+(2*8)+(1*3)=112
112 % 10 = 2
So 1008119-83-2 is a valid CAS Registry Number.

1008119-83-2 Well-known Company Product Price

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  • Sigma

  • (SML0522)  JM6  ≥97% (HPLC)

  • 1008119-83-2

  • SML0522-5MG

  • 1,301.04CNY

  • Detail

  • Sigma

  • (SML0522)  JM6  ≥97% (HPLC)

  • 1008119-83-2

  • SML0522-25MG

  • 5,253.30CNY

  • Detail

1008119-83-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 10, 2017

Revision Date: Aug 10, 2017

1.Identification

1.1 GHS Product identifier

Product name 3,4-Dimethoxy-N-[4-(3-nitrophenyl)-5-(1-piperidinylmethyl)-1,3-th iazol-2-yl]benzenesulfonamide

1.2 Other means of identification

Product number -
Other names 3,4-Dimethoxy-N-[4-(3-nitrophenyl)-5-(1-piperidinylmethyl)-2-thiazolyl]-benzenesulfonamide

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1008119-83-2 SDS

1008119-83-2Upstream product

1008119-83-2Downstream Products

1008119-83-2Relevant academic research and scientific papers

SMALL MOLECULE INHIBITORS OF KYNURENINE-3-MONOOXYGENASE

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Page/Page column 62, (2008/06/13)

The present invention relates to compounds of formula (Ia) or (Ib) and their tautomers and/or pharmaceutically acceptable salts and compositions and methods of uses thereof.

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