100812-01-9Relevant academic research and scientific papers
Asymmetric Induction in the Addition of Grignard Reagents to Nitrones
Cowling, Martin P.,Jenkins, Paul R.,Cooper, Kelvin
, p. 1503 - 1504 (2007/10/02)
Grignard reagents add to N-(2-phenylpropylidene)cyclohexanamine N-oxide with significant asymmetric induction; an X-ray structure of one product demonstrates that the addition proceeds according to Cram's rule.
Preparation of Vicinal N-Alkylamino Alcohols via Acylation-Rearrangement of Nitrones Followed by Hydride Reduction
Coates, Robert M.,Cummins, Clark H.
, p. 1383 - 1389 (2007/10/02)
Acylation-rearrangement of N-tert-butyl and N-cyclohexyl nitrones of cyclohexanecarboxaldehyde (1), n-butyraldehyde, isobutyraldehyde, 3-cyclohexenecarboxaldehyde, and α-methylpropionaldehyde gave α-pivaloyloxy imines, which underwent reduction with lithi
