1008131-84-7Relevant articles and documents
Direct entry to peptidyl ketones via SmI2-mediated C-C bond formation with readily accessible N-peptidyl oxazolidinones
Mittag, Tina,Christensen, Kasper L.,Lindsay, Karl B.,Nielsen, Niels Christian,Skrydstrup, Troels
, p. 1088 - 1092 (2008/09/18)
(Chemical Equation Presented) In this work, a new method for the preparation of peptidyl ketones is presented employing a SmI2/H 2O-mediated coupling of N-peptidyl oxazolidinones with electron-deficient alkenes. The requisite peptide