1008138-66-6 Usage
General Description
2-Methyl-5-nitro-pyridine-boronic acid pinacol ester is a chemical compound that is used in the pharmaceutical and chemical industries. It is a boronic acid derivative that contains a nitro group and a pyridine ring, making it useful in various organic synthesis reactions. 2-METHYL-5-NITRO-PYRIDINE-BORONIC ACID PINACOL ESTER is often employed in the production of pharmaceuticals, agrochemicals, and fine chemicals, as it can act as a building block for more complex molecules. The pinacol ester functionality provides stability and solubility, making it suitable for use in a wide range of chemical reactions and applications. Additionally, the presence of the boronic acid group allows for the compound to participate in Suzuki-Miyaura cross-coupling reactions, which are widely used in the synthesis of biaryl compounds. Overall, 2-Methyl-5-nitro-pyridine-boronic acid pinacol ester is a versatile and important chemical building block with various applications in the pharmaceutical and chemical industries.
Check Digit Verification of cas no
The CAS Registry Mumber 1008138-66-6 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,0,8,1,3 and 8 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1008138-66:
(9*1)+(8*0)+(7*0)+(6*8)+(5*1)+(4*3)+(3*8)+(2*6)+(1*6)=116
116 % 10 = 6
So 1008138-66-6 is a valid CAS Registry Number.
1008138-66-6Relevant articles and documents
Design and Discovery of N-(2-Methyl-5′-morpholino-6′-((tetrahydro-2H-pyran-4-yl)oxy)-[3,3′-bipyridin]-5-yl)-3-(trifluoromethyl)benzamide (RAF709): A Potent, Selective, and Efficacious RAF Inhibitor Targeting RAS Mutant Cancers
Nishiguchi, Gisele A.,Rico, Alice,Tanner, Huw,Aversa, Robert J.,Taft, Benjamin R.,Subramanian, Sharadha,Setti, Lina,Burger, Matthew T.,Wan, Lifeng,Tamez, Victoriano,Smith, Aaron,Lou, Yan,Barsanti, Paul A.,Appleton, Brent A.,Mamo, Mulugeta,Tandeske, Laura,Dix, Ina,Tellew, John E.,Huang, Shenlin,Mathews Griner, Lesley A.,Cooke, Vesselina G.,Van Abbema, Anne,Merritt, Hanne,Ma, Sylvia,Gampa, Kalyani,Feng, Fei,Yuan, Jing,Wang, Yingyun,Haling, Jacob R.,Vaziri, Sepideh,Hekmat-Nejad, Mohammad,Jansen, Johanna M.,Polyakov, Valery,Zang, Richard,Sethuraman, Vijay,Amiri, Payman,Singh, Mallika,Lees, Emma,Shao, Wenlin,Stuart, Darrin D.,Dillon, Michael P.,Ramurthy, Savithri
, p. 4869 - 4881 (2017/06/28)
RAS oncogenes have been implicated in >30% of human cancers, all representing high unmet medical need. The exquisite dependency on CRAF kinase in KRAS mutant tumors has been established in genetically engineered mouse models and human tumor cells. To date
