1008144-94-2Relevant articles and documents
Chemotherapeutic bone-targeted bisphosphonate prodrugs with hydrolytic mode of activation
Erez, Rotem,Ebner, Sharon,Attali, Bernard,Shabat, Doron
, p. 816 - 820 (2008/09/16)
Osseous tissues are considered to be limited as therapeutic target sites due to their biological properties. We have designed and synthesized two kinds of hydrolytically activated chemotherapeutic prodrugs containing bisphosphonate, a bone-targeting moiet