1008361-77-0

Basic information

• Product Name: 3-BROMO-6-IODO-2-METHYLPYRIDINE
• Synonyms: 3-BROMO-6-IODO-2-METHYLPYRIDINE
• CAS NO: 1008361-77-0
• Molecular Formula: C6H5BrIN
• Molecular Weight: 297.91907
• Mol File: 1008361-77-0.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 264℃
• Flash Point: 114℃
• Appearance: /
• Density: 2.171
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: 0.21±0.10(Predicted)
• CAS DataBase Reference: 3-BROMO-6-IODO-2-METHYLPYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-BROMO-6-IODO-2-METHYLPYRIDINE(1008361-77-0)
• EPA Substance Registry System: 3-BROMO-6-IODO-2-METHYLPYRIDINE(1008361-77-0)

Safety Data

• Hazardous Substances Data: 1008361-77-0(Hazardous Substances Data)

Usage

General Description

3-Bromo-6-iodo-2-methylpyridine is a compound with the chemical formula C6H5BrIN. It is a heterocyclic compound that contains both bromine and iodine atoms. 3-Bromo-6-iodo-2-methylpyridine is often used as a building block in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds. Its unique structure and reactivity make it a valuable intermediate in organic chemistry, allowing for the creation of diverse and complex molecules. 3-Bromo-6-iodo-2-methylpyridine has also been studied for its potential biological activities and is of interest in the development of new drugs and therapeutic agents. Its properties make it a versatile and important compound in the field of organic and medicinal chemistry.

Upstream product

• 42753-71-9 5-bromo-6-methyl-pyridin-2-ylamine 
• 39919-65-8 2,5-dibromo-6-methylpyridine 

Downstream Products

• 137778-18-8 5-bromo-6-methyl-pyridine-2-carbaldehyde 
• 1228013-15-7 1-ethyl-7-(2-methyl-6-(4H-1,2,4-triazol-3-yl)pyridin-3-yl)-3,4-dihydropyrazino[2,3-b]pyrazin-2(1H)-one 
• 1173897-86-3 5-bromo-6-methylpyridine-2-carbonitrile 

Relevant articles and documents

Povarov reaction, scope and limitations: Preparation of diversely heterocyclic tetrahydro-1H-cyclopenta[c]quinolines

Parallel synthesis of diverse heterocyclic-tetrahydro-1H-cyclopenta[c]quinolines in excellent yields and high endo diastereoselectivity has been described hereia These compounds are highly functionalized natural product-like tricyclic systems, which may be useful as biologically relevant targets. Fine tuning of the reaction conditions need to be performed depending on the nature and molecular structure of the heterocyclic aromatic carbaldehyde, as well as the choice of the Lewis acid catalyst. Synthesis of the heterocyclic aromatic aldehyde precursors of the Povarov Reaction is also described.

PHARMACEUTICAL FORMULATIONS, PROCESSES, SOLID FORMS AND METHODS OF USE RELATING TO 1-ETHYL-7-(2-METHYL-6-(1H-1,2,4-TRIAZOL-3-YL)PYRIDIN-3-YL)-3,4-DIHYDROPYRAZINO[2,3-b]PYRAZIN-2(1H)-ONE

Provided herein are formulations, processes, solid forms and methods of use relating to 1-ethyl-7-(2-methyl-6-(1H-1,2,4-triazol-3-yl)pyridin-3-yl)-3,4-dihydropyrazino[2,3-b]pyrazin-2(1H)-one.

SUBSTITUTED TRICYCLIC COMPOUNDS WITH ACTIVITY TOWARDS EP1 RECEPTORS

The present invention belongs to the field of EP1 receptor ligands. More specifically it refers to compounds of general formula (I) having great affinity and selectivity for the EP1 receptor. The invention also refers to the process for their preparation, to their use as medicament for the treatment and/or prophylaxis of diseases or disorders mediated by the EP1 receptor as well as to pharmaceutical compositions comprising them.