100845-90-7

Usage

Uses

Used in Pharmaceutical Industry:
Cyclopropanecarboxaldehyde, 1-(4-chlorophenyl)is used as an intermediate in the synthesis of enantiomerically and diastereomerically enriched cyclobutane amines and amides. These compounds are of significant interest in the pharmaceutical industry due to their potential applications as therapeutic agents for various medical conditions. The unique structural features of Cyclopropanecarboxaldehyde, 1-(4-chlorophenyl)- enable the development of novel drugs with improved efficacy and selectivity.
Used in Chemical Synthesis:
In the field of organic chemistry, Cyclopropanecarboxaldehyde, 1-(4-chlorophenyl)serves as a valuable building block for the synthesis of a wide range of chemical products. Its reactive functional groups, such as the formyl group and the 4-chlorophenyl group, can be further modified or functionalized to produce a variety of derivatives with diverse applications in different industries, including pharmaceuticals, agrochemicals, and materials science.
Used in Research and Development:
Cyclopropanecarboxaldehyde, 1-(4-chlorophenyl)is also utilized in research and development for the exploration of new synthetic routes and methodologies. Its unique structural features make it an attractive candidate for studying various chemical reactions and mechanisms, which can lead to the discovery of new synthetic strategies and the development of novel compounds with potential applications in various fields.

Upstream product

• 30568-32-2 2-(4-chlorophenyl)-2-methylpropanenitrile 
• 64399-27-5 1-(4-chlorophenyl)-1-cyclopropanecarbonitrile 
• 80866-81-5 1-(4-chlorophenyl)-1-cyclopropanemethanol 
• 1271656-15-5 C₁₂H₁₄ClNO₂ 
• 140-53-4 p-chlorobenzyl cyanide 
• 72934-37-3 3-(4-chlorophenyl)-1-cyclopropanecarboxylic acid 

Downstream Products

• 246233-62-5 1-(4-chlorophenyl)-1-(2-fluoro-2-(methoxycarbonyl)ethenyl)cyclopropane 
• 200354-36-5 3-[1-(p-chlorophenyl)-cyclopropyl]-2-fluoro-2-propen-1-ol 
• 246233-81-8 1-(3-acetoxy-2-fluoroprop-1-enyl)-1-(4-chlorophenyl)cyclopropane 
• 100846-09-1 1-(4-chlorophenyl)-1-(E-3-(3-phenoxyphenyl)-prop-1-en-3-onyl)-cyclopropane 
• 1205639-03-7 (S)-4-{(Z)-2-[1-(4-chloro-phenyl)-cyclopropyl]-vinyl}-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester 

Relevant academic research and scientific papers

COMPOUNDS FOR TREATING AND PREVENTING GROWTH HORMONE RECEPTOR-DEPENDENT CONDITIONS

The invention relates to compounds, in particular pyrimidine-2,4-diamines, analogues and salts thereof and pharmaceutical compositions comprising pyrimidine-2,4-diamines analogues and salts thereof for use in the treatment and prevention of a disease, in particular a growth hormone receptor-dependent condition. The invention also relates to methods of using these compounds and compositions to treat physiological dsorders related to the amount or activity of growth hormone. In a particular embodiment, the invention relates to a compound according to formula 1 for use in the treatment or prevention of a disease in a subject

Photochemical Deracemization at sp3-Hybridized Carbon Centers via a Reversible Hydrogen Atom Transfer

A photochemical deracemization of 5-substituted 3-phenylimidazolidine-2,4-diones (hydantoins) is reported (27 examples, 69%-quant., 80–99% ee). The reaction is catalyzed by a chiral diarylketone which displays a two-point hydrogen bonding site. Mechanistic evidence (DFT calculations, radical clock experiments, H/D labeling) suggests the reaction to occur by selective hydrogen atom transfer (HAT). Upon hydrogen binding, one substrate enantiomer displays the hydrogen atom at the stereogenic center to the photoexcited catalyst allowing for a HAT from the substrate and eventually for its conversion into the product enantiomer. The product enantiomer is not processed by the catalyst and is thus enriched in the photostationary state.

C-3 NOVEL TRITERPENONE WITH C-28 UREA DERIVATIVES AS HIV INHIBITORS

The present invention relates to C-3 novel triterpenone with C-28 urea derivatives of formula (I); or pharmaceutically acceptable salts, pharmaceutically acceptable solvates, pharmaceutically acceptable hydrates, tautomers, stereoisomers, prodrugs, compositions or combination thereof, wherein R1, R2, R3, W, J and X are as defined herein. The present invention also relates to pharmaceutical compositions comprising compounds of formula (I) useful for the treatment of viral diseases and particularly HIV mediated diseases.

C-3 NOVEL TRITERPENONE WITH C-28 REVERSE AMIDE DERIVATIVES AS HIV INHIBITORS

Formula (I) The invention relates to C-3 novel triterpenone with C-28 reverse amide derivatives, related compounds, and pharmaceutical compositions useful for the therapeutic treatment of viral diseases and particularly HIV mediated diseases.

1-ADAMANTYLAZETIDIN-2-ONE DERIVATIVES AND DRUGS CONTAINING SAME

It is to provide a novel compound useful for preventing and/or treating diseases that involves 11β-hydroxysteroid dehydrogenase 1, particularly diabetes, insulin resistance, diabetes complication, obesity, dyslipidemia, hypertension, fatty liver, or metab

Modulators of 11- beta hydroxyl steroid dehydrogenase type 1, pharmaceutical compositions thereof, and methods of using the same

The present invention relates to inhibitors of 11-β hydroxyl steroid dehydrogenase type 1 and pharmaceutical compositions thereof. The compounds of the invention can be useful in the treatment of various diseases associated with expression or activity of 11-β hydroxyl steroid dehydrogenase type 1.

Methods and compositions for protecting animals and humans against attack and infestation by arthropod and helminth parasites

The present invention relates to methods and compositions for treating animals and humans, and for controlling, preventing and protecting animals and humans from infestation and infection by arthropod and helminth parasites by administering or applying to

1, 4-diaryl-2-fluoro-2-butene insecticidal and acaricidal agents

Pesticidal 1,4-diaryl-2-fluoro-2-butene compounds having the structural formula I STR1 and compositions and methods comprising those compounds for the control of insect and acarid pests.

Methods and compositions for protecting animals and humans against attack and infestation by arthropod and helminth parasites

The present invention relates to methods and compositions for treating animals and humans, and for controlling, preventing and protecting animals and humans from infestation and infection by arthropod and helminth parasites by administering or applying to

1,4,diaryl-2-fluoro-2-butene insecticidal and acaricidal agents

Pesticidal 1,4-diaryl-2-fluoro-2-butene compounds having the structural formula I STR1 and compositions and methods comprising those compounds for the control of insect and acarid pests.