1008463-86-2Relevant academic research and scientific papers
One-step synthesis of substituted dihydro- and tetrahydroisoquinolines by FeCl3·6H2O catalyzed intramolecular Friedel-Crafts reaction of benzylamino-substituted propargylic alcohols
Huang, Wen,Shen, Quansheng,Wang, Jialiang,Zhou, Xigeng
, p. 1586 - 1589 (2008)
(Chemical Equation Presented) A mild, versatile, and efficient method for the one-step synthesis of substituted dihydro- and tetrahydroisoquinolines has been developed by the FeCl3·6H2O catalyzed intramolecular allenylation/cyclization reaction of benzylamino-substituted propargylic alcohols, representing the first example of the intramolecular Friedel-Crafts reaction of propargylic alcohols.
