1008517-73-4

Basic information

• Product Name: 5-(benzyloxy)pyridazin-3(2H)-one
• Synonyms: 5-(benzyloxy)pyridazin-3(2H)-one;5-(Benzyloxy)-3(2H)-pyridazinone
• CAS NO: 1008517-73-4
• Molecular Formula: C₁₁H₁₀N₂O₂
• Molecular Weight: 202
• Mol File: 1008517-73-4.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 5-(benzyloxy)pyridazin-3(2H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(benzyloxy)pyridazin-3(2H)-one(1008517-73-4)
• EPA Substance Registry System: 5-(benzyloxy)pyridazin-3(2H)-one(1008517-73-4)

Safety Data

• Hazardous Substances Data: 1008517-73-4(Hazardous Substances Data)

Usage

Description

5-(benzyloxy)pyridazin-3(2H)-one is a pyridazinone derivative, a heterocyclic compound characterized by a six-membered ring with two nitrogen atoms and one oxygen atom. This specific compound is distinguished by the presence of a benzyloxy group attached to the fifth carbon of the pyridazinone ring, giving it the molecular formula C14H11N3O2. It holds promise in the field of medicinal chemistry for its potential pharmaceutical applications due to its notable biological activities.

Uses

Used in Pharmaceutical Industry:
5-(benzyloxy)pyridazin-3(2H)-one is utilized as a pharmaceutical intermediate for the development of new drugs, leveraging its biological activities. Its specific role in drug development may vary, but it is particularly valued for its potential to contribute to the creation of novel therapeutic agents.
The synthesis and purification processes of 5-(benzyloxy)pyridazin-3(2H)-one can significantly influence its properties and uses, making it a versatile compound in the ongoing quest for new medicinal solutions.

Upstream product

• 1008517-75-6 5-benzyloxy-2-(tetrahydro-pyran-2-yl)-2H-pyridazin-3-one 
• 100-51-6 benzyl alcohol 

Downstream Products

• 1453500-06-5 5-benzyloxy-2-[2-(4-bromomethyl-2-methyl-phenyl)-2-oxo-ethyl]-2H-pyridazin-3-one 
• 1008518-06-6 5-benzyloxy-2-[2-(4-bromomethyl-phenyl)-2-oxo-ethyl]-2H-pyridazin-3-one 
• 1453499-58-5 5-(benzyloxy)-2-(2-(4-((dimethylamino)methyl)-2-methylphenyl)-2-oxoethyl)pyridazin-3(2H)-one 
• 1453500-05-4 5-benzyloxy-2-[2-(4-hydroxymethyl-2-methyl-phenyl)-2-oxo-ethyl]-2H-pyridazin-3-one 
• 1008518-05-5 5-benzyloxy-2-[2-(4-hydroxymethyl-phenyl)-2-oxo-ethyl]-2H-pyridazin-3-one 

Relevant articles and documents

Design, synthesis and evaluation of MCH receptor 1 antagonists - Part III: Discovery of pre-clinical development candidate BI 186908

Abstract Although overweight and obesity are highly prevalent conditions, options to treat them are still very limited. As part of our search for safe and effective MCH-R1 antagonists for the treatment of obesity, two series of pyridones and pyridazinones

NEW PYRIDONE DERIVATIVES WITH MCH ANTAGONISTIC ACTIVITY AND MEDICAMENTS COMPRISING THESE COMPOUNDS

The present invention relates to compounds of general formula (I) wherein the groups and radicals B, k, L, U,V, W, X, Y, Z, R1, R2, have the meanings given in claim 1. Moreover the invention relates to pharmaceutical compositions containing at least one compound according to the invention. By virtue of their MCH- receptor antagonistic activity the pharmaceutical compositions according to the invention are suitable for the treatment of metabolic disorders and/or eating disorders, particularly obesity, bulimia, anorexia, hyperphagia and diabetes.