1008526-84-8

Basic information

• Product Name: 4H-1,2,4-Triazole-4-ethanamine
• Synonyms: 4H-1,2,4-Triazole-4-ethanamine;2-(4H-1,2,4-TRIAZOL-4-YL)ETHANAMINE;2-(4H-1,2,4-triazol-4-yl)ethanamine(SALTDATA: 2HCl);4-(2-AMinoethyl)-4H-1,2,4-triazole
• CAS NO: 1008526-84-8
• Molecular Formula: C4H8N4
• Molecular Weight: 112
• Product Categories: API intermediates
• Mol File: 1008526-84-8.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 266.3 °C at 760 mmHg
• Flash Point: 114.9 °C
• Appearance: /
• Density: 1.31 g/cm³
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• PKA: 7.38±0.10(Predicted)
• CAS DataBase Reference: 4H-1,2,4-Triazole-4-ethanamine(CAS DataBase Reference)
• NIST Chemistry Reference: 4H-1,2,4-Triazole-4-ethanamine(1008526-84-8)
• EPA Substance Registry System: 4H-1,2,4-Triazole-4-ethanamine(1008526-84-8)

Safety Data

• Hazardous Substances Data: 1008526-84-8(Hazardous Substances Data)

Usage

Description

4H-1,2,4-Triazole-4-ethanamine is a complex organic compound that belongs to the triazole family. It is known for its diverse set of properties, which makes it suitable for various applications across different industries.

Uses

Used in Pharmaceutical Industry:
4H-1,2,4-Triazole-4-ethanamine is used as a building block for creating medications with a wide range of medicinal properties. It is particularly valuable for developing drugs with antimicrobial, antiviral, and anticancer effects.
Used in Organic Synthesis:
4H-1,2,4-Triazole-4-ethanamine is used as a precursor for synthesizing various other compounds, making it an essential component in the field of organic synthesis.
Used in Chemical Research:
4H-1,2,4-Triazole-4-ethanamine is used as a research tool in chemical laboratories, where it aids in the exploration of new chemical reactions and the development of novel compounds.
Safety Precautions:
It is important to handle 4H-1,2,4-Triazole-4-ethanamine with care due to its potential hazards. The handling, usage, and disposal of this compound should always adhere to the appropriate safety guidelines to minimize risks.

Upstream product

• 288-88-0 1,2,4-Triazole 
• 689-98-5 chloroethylamine 

Relevant articles and documents

ALKYLATION OF AZOLES USING beta -FUNCTIONAL ALKYL HALIDES UNDER CONDITIONS OF PHASE TRANSFER CATALYSIS.

The objective of this study was to develop a convenient synthetic method for direct N-alkylation of pyrazole (I), 3(5)-methylpyrazole (II), 3,5-dimethylpyrazole (III), 1,2,4-triazole (IV), and tetrazole (V) using beta -functional alkyl halides under conditions of two-phase catalysis and with high product yields. This investigation was stimulated by the fact that the desired reaction products are intermediates in the synthesis of an important class of compounds, vinylazole, as well as of various pharmaceutical agents. It is found that depending on the acidity of the azole, alkylation with dichloroethane can be accompanied by beta -elimination. The effect of solvent on the course of alkylation reactions using dichloroethane has also been studied, and revealed that the reactions occur via the intermediacy of ion pairs rather than free anions.