100853-10-9Relevant academic research and scientific papers
Use of the Two Enantiometers of 7,7-Dimethylbicyclohept-2-en-6-one to form Complementary Optically Active Synthons in a Convergent Synthesis of Leukotriene-B4
Cotterill, Ian C.,Jaouhari, Rabih,Dorman, Gyoergy,Roberts, Stanley M.,Scheinmann, Feodor,Wakefield, Basil J.
, p. 2505 - 2512 (2007/10/02)
The acetate (+/-)-4 was resolved by an enantioselective hydrolysis catalysed by porcine pancreatic lipase.The resultant alcohol (-)-3 and the optically active ester (+)-4 were converted into the ketones (+)-2 and (-)-2 respectively.The ketone (+)-2 was el
Synthesis of (3S,4R)-Eldanolide and (5S,12R)-Leukotriene-B4 through Photolysis of Optically Active Hydroxy-7,7-dimethylbicycloheptanones
Davies, H. Geoff,Roberts, Stanley M.,Wakefield, Basil J.,Winders, John A.
, p. 1166 - 1168 (2007/10/02)
Photoisomerisation of 3-hydroxy-7,7-dimethylbicycloheptan-6-ones is the key step in a new route to the pheromone eldanolide while leukotriene-B4 is available through a photolytic retro reaction of 2-hydroxy-7,7-dimethylbicycloheptan-6-ones.
