100860-96-6 Usage
Classification
dissociative anesthetic
Medical uses
anesthesia, sedation
Mechanism of action
blocks the effects of the neurotransmitter glutamate in the brain
Effects
dissociative anesthesia, analgesia
Other potential uses
antidepressant, anti-inflammatory, depression, chronic pain
Risks
potential for abuse, recreational use, addiction.
Check Digit Verification of cas no
The CAS Registry Mumber 100860-96-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,0,8,6 and 0 respectively; the second part has 2 digits, 9 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 100860-96:
(8*1)+(7*0)+(6*0)+(5*8)+(4*6)+(3*0)+(2*9)+(1*6)=96
96 % 10 = 6
So 100860-96-6 is a valid CAS Registry Number.
100860-96-6Relevant articles and documents
Synthesis of 2,6-diaryl-substituted pyridines and their antitumor activities
Son, Jong-Keun,Zhao, Long-Xuan,Basnet, Arjun,Thapa, Pritam,Karki, Radha,Na, Younghwa,Jahng, Yurngdong,Jeong, Tae Cheon,Jeong, Byeong-Seon,Lee, Chong-Soon,Lee, Eung-Seok
, p. 675 - 682 (2008)
For the development of novel antitumor agents, we designed and synthesized 2,6-diaryl-substituted pyridine derivatives bearing three aryl groups, which are the bioisosteres of terpyridine, and evaluated their biological activities. Most of the 18 prepared compounds showed moderate cytotoxicity against several human cancer cell lines. From the structure-activity relationships we may conclude that the number of aryl groups employed would be critical for their biological activities.
