100869-07-6 Usage
General Description
2-Aminomethyl-4-methyl-pentanoic acid is a chemical compound with the molecular formula C8H17NO2. It is an amino acid derivative, also known as L-valine. 2-AMINOMETHYL-4-METHYL-PENTANOIC ACID is a non-proteinogenic amino acid, meaning it is not used for protein synthesis in the body. L-valine is an essential amino acid, meaning it cannot be synthesized by the body and must be obtained from the diet. It plays a crucial role in promoting muscle growth and tissue repair, making it an important component in sports nutrition and dietary supplements. Additionally, L-valine has been linked to improved immune function and may offer potential benefits for individuals with liver and gallbladder disorders.
Check Digit Verification of cas no
The CAS Registry Mumber 100869-07-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,0,8,6 and 9 respectively; the second part has 2 digits, 0 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 100869-07:
(8*1)+(7*0)+(6*0)+(5*8)+(4*6)+(3*9)+(2*0)+(1*7)=106
106 % 10 = 6
So 100869-07-6 is a valid CAS Registry Number.
100869-07-6Relevant articles and documents
Evaluation of several routes to advanced pregabalin intermediates: Synthesis and enantioselective enzymatic reduction using ene-reductases
Debarge, Sebastien,McDaid, Paul,O'Neill, Pat,Frahill, James,Wong, John W.,Carr, Donncha,Burrell, Adam,Davies, Simon,Karmilowicz, Mike,Steflik, Jeremy
, p. 109 - 121 (2014)
This publication describes the evaluation of four synthetic routes to the advanced pregabalin (Lyrica) intermediate 7. Asymmetric reduction of (E)-7 with an ene-reductase (OPR1 from Lycopersicon esculentum) gave a saturated cyanoester intermediate 5 with the desired S stereocenter in ≥99% ee. OPR1 also catalyzed the reduction of (Z)-7 to (S)-5, but with lower conversion and selectivity.
