1008754-64-0Relevant academic research and scientific papers
Highly enantioselective α-aminoxylation of aldehydes and ketones with a polymer-supported organocatalyst
Font, Daniel,Bastero, Amaia,Sayalero, Sonia,Jimeno, Ciril,Pericas, Miquel A.
, p. 1943 - 1946 (2007)
The first catalytic enantioselective α-aminoxylation of aldehydes and ketones using an insoluble, polymer-supported organocatalyst (1) derived from trans-4-hydroxyproline is reported (ee: 96-99%). Reaction rates in the aminoxylation of cyclic ketones with 1 are higher than those reported with L-proline. The insoluble nature of 1 simplifies workup conditions and allows catalyst recycling without an apparent decrease in enantioselectivity or yield.
A highly selective, organocatalytic route to chiral dihydro-1,2-oxazines
Kumarn, Sirirat,Shaw, David M.,Longbottom, Deborah A.,Ley, Steven V.
, p. 4189 - 4191 (2007/10/03)
(Chemical Equation Presented) The organocatalyzed asymmetric synthesis of chiral dihydro-1,2-oxazines from achiral starting materials proceeds in moderate to excellent yields and excellent enantioselectivity. This sequential reaction gives the desired pro
