100890-80-0Relevant academic research and scientific papers
ISOMERIZATION OF FLUORINE-CONTAINING β-AMINOVINYL THIOKETONES AND KETONES
Filyakova, V. I.,Busygin, I. G.,Pashkevich, K. I.
, p. 1685 - 1687 (2007/10/02)
The previously unknown irreversible rearrangement of β-aminovinyl thioketones and ketones with the amino group and the fluoroalkyl substituent in the gem position to β-aminovinyl thioketones and ketones with the groups in the γ position was discovered.The alkyl-substituted compounds isomerize more readily than the aryl derivatives having the same fluoroalkyl substituent, while the β-aminovinyl thioketones isomerize more readily than the oxygen analogs (β-aminovinyl ketones).Data which favor an intermolecular mechanism for the rearrangement are presented.
THE REACTIONS OF AMINO AND THIO DERIVATIVES OF POLYFLUORINATED β-DIKETONES WITH AMINES
Busigin, I. G.,Pashkevich, K. I.
, p. 1270 - 1274 (2007/10/02)
A study was carried out on the aminolysis of isomeric polyfluorinated β-aminovinylthiones and monothio-β-diketones with geminal fluoroalkyl and mercapto groups. β-Aminovinylthiones react with amines at the enamine electrophilic site, while monothio-β-diketones react at the electrophilic site attached to the nonfluorinated substituent.Intrachelate prototropic tautomerism is presumably one of the factors responsible for the reaction regiospecificity.
