100895-89-4

Upstream product

• 100895-84-9 (2R,3R,4R)-3,5-Dibenzyloxy-4-methyl-1,2-pentanediol 
• 100895-82-7 (2R,3R,4R)-3,5-Dibenzyloxy-1,2-O-isopropylidene-4-methyl-1,2-pentanediol 
• 82414-51-5 (E)-(2R,3S)-2-Methyl-5-phenyl-pent-4-ene-1,3-diol 
• 92979-23-2 C₂₆H₂₈O₂ 
• 67498-12-8 (E)-(2S,3S)-3-Hydroxy-2-methyl-5-phenyl-pent-4-enoic acid methyl ester 
• 92979-24-3 (2R,3R)-2,4-Bis-benzyloxy-3-methyl-butyraldehyde 
• 100-44-7 benzyl chloride 
• 98575-61-2 (2R,3R,4S)-1,2-O-isopropylidene-4-methylpentane-1,2,3,5-tetraol 
• 92979-24-3 (2R,3R)-2,4-Bis-benzyloxy-3-methyl-butyraldehyde 

Relevant academic research and scientific papers

Addition of Crotylchromium(II) and Dilithium Propionate to (R)-2,3-O-isopropylideneglyceraldehyde: Steric Course and Synthetic Application in a Formal Synthesis of (+)- and (-)-δ-Multistriatin

The chromium(II) salt 4a of crotyl bromide adds to (R)-2,3-O-isopropylideneglyceraldehyde (1) with high enantiofacial and low diastereofacial (i.e.Cram) selectivity, whereas dilithium propionate (9) shows the opposite behaviour.The adducts 5, 7, and 10 can be used in a formal synthesis of both enantiomers of the insect pheromone δ-multistriatin (30).

STEREOSELECTIVE ADDITIONS TO CARBOXYLIC ACID DIANIONS AND β-LACTONE SUBSTITUTED ESTER ENOLATES. APPLICATION TO THE SYNTHESIS OF RACEMIC EPI-BLASTMYCINONE, δ-MULTISTRIATINE, PARACONIC ESTERS AND LIGNANTYPE DILACTONES

New stereoselective syntheses are reported for racemic 4-epi-blastmycinone (6) and δ-multistriatine (13) utilizing the anti-configurated γ,δ-unsaturated β-hydroxy-carboxylic acids 2a/b.A diastereo- and enantioselective aldoltype addition of phenylacetic acid dianion to benzaldehyde has been achaived by employing optically active alkoxide amide bases.Finally, highly stereocontrolled additions to the novel β-lactone substituted ester enolates 22 are described.