1009-57-0 Usage
Uses
Used in Organic Synthesis:
1-(5-amino-4-nitrothiophen-2-yl)ethanone is utilized as a key intermediate in organic synthesis for the preparation of a wide array of chemical compounds. Its presence of both amino and nitro groups, along with the ketone functionality, allows for multiple reaction pathways, making it a preferred choice for constructing complex organic molecules.
Used in Pharmaceutical Research:
In the pharmaceutical industry, 1-(5-amino-4-nitrothiophen-2-yl)ethanone is employed as a building block for the development of new drugs. Its unique structure and functional groups enable the design of molecules with potential therapeutic properties, contributing to the discovery of novel pharmaceutical agents.
Used in Laboratory Settings:
1-(5-amino-4-nitrothiophen-2-yl)ethanone is also used in academic and research laboratories for studying chemical reactions and exploring the scope of its reactivity. The presence of different functional groups on the thiophene ring provides opportunities for various synthetic transformations, which are crucial for advancing the understanding of chemical processes and mechanisms.
Check Digit Verification of cas no
The CAS Registry Mumber 1009-57-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,0,0 and 9 respectively; the second part has 2 digits, 5 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1009-57:
(6*1)+(5*0)+(4*0)+(3*9)+(2*5)+(1*7)=50
50 % 10 = 0
So 1009-57-0 is a valid CAS Registry Number.
1009-57-0Relevant academic research and scientific papers
Preparation of 2-halo-3-nitro-5-acyl thiophenes and intermediate compounds
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, (2008/06/13)
Disclosed are novel intermediates and their preparation, and the preparation therefrom of 2-halo-3-nitro-5-acyl thiophenes which themselves are important intermediates for the preparation of azo dyes of the type, STR1 wherein C1 represents typically any aniline, tetrahydroquinoline, benzomorpholine or the like coupler and the acyl group contains from 1-10 carbons. It has been found that if 2-acyl thiophene is treated with a hydroxylamine compound, e.g., a salt of hydroxylamine, including sulphate, chloride or the like, to form the oxime prior to the 2-position halogenation and 3-position nitration steps, various side reactions such as halogenation of the acyl group and nitration of the 5-position are avoided, the yield of each step is improved, and the reactions are less sensitive to the deleterious effects of temperature variations and excess reactants. The oxime derivative is readily reconverted to the acyl derivative after the halogenation and nitration steps have been completed. This product is then readily aminated to give the 2-amino derivative.
