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NA-CBZ-ARG-ARG 4-METHOXY-B-NAPHTHYLAMIDE, also known as N-alpha-CBZ-L-arginyl-L-arginine 4-Methoxy-beta-naphthylamide, Acetate Salt, is a synthetic compound designed as a specific substrate for the enzyme cathepsin B. It is characterized by its ability to be cleaved by cathepsin B, resulting in a fluorescent product that can be easily detected and measured. This property makes it a valuable tool in the study and analysis of cathepsin B activity.

100900-19-4

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100900-19-4 Usage

Uses

Used in Research and Diagnostic Applications:
NA-CBZ-ARG-ARG 4-METHOXY-B-NAPHTHYLAMIDE is used as a fluorogenic substrate for cathepsin B, allowing researchers to study the activity and function of this enzyme in various biological processes. The enzyme cathepsin B is involved in several cellular functions, including protein degradation, antigen presentation, and tumor progression. By using this substrate, researchers can gain insights into the role of cathepsin B in these processes and potentially develop targeted therapies for related conditions.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, NA-CBZ-ARG-ARG 4-METHOXY-B-NAPHTHYLAMIDE is used as a tool to screen and identify potential inhibitors of cathepsin B. This is important because cathepsin B has been implicated in various diseases, such as cancer, where its inhibition could lead to therapeutic benefits. By using this substrate, researchers can test the effectiveness of different compounds in inhibiting cathepsin B, which may eventually lead to the development of new drugs targeting this enzyme.
Used in Drug Delivery Systems:
Similar to gallotannin, NA-CBZ-ARG-ARG 4-METHOXY-B-NAPHTHYLAMIDE can also be employed in the development of novel drug delivery systems. These systems can be designed to specifically target cathepsin B, allowing for more efficient and targeted delivery of therapeutic agents. This could potentially improve the efficacy of treatments and reduce side effects by ensuring that the drug is only released in the presence of the target enzyme.

Check Digit Verification of cas no

The CAS Registry Mumber 100900-19-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,0,9,0 and 0 respectively; the second part has 2 digits, 1 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 100900-19:
(8*1)+(7*0)+(6*0)+(5*9)+(4*0)+(3*0)+(2*1)+(1*9)=64
64 % 10 = 4
So 100900-19-4 is a valid CAS Registry Number.

100900-19-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 10, 2017

Revision Date: Aug 10, 2017

1.Identification

1.1 GHS Product identifier

Product name acetic acid,benzyl N-[(2S)-5-(diaminomethylideneamino)-1-[[(2S)-5-(diaminomethylideneamino)-1-[(4-methoxynaphthalen-2-yl)amino]-1-oxopentan-2-yl]amino]-1-oxopentan-2-yl]carbamate

1.2 Other means of identification

Product number -
Other names Z-Arg-Arg 4-methoxy-|A-naphthylamide acetate salt

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:100900-19-4 SDS

100900-19-4Upstream product

100900-19-4Downstream Products

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