100905-99-5

Upstream product

• 102854-63-7 4-trifluoromethyl-2-(5H)-furanone 
• 60656-87-3 benzyloxyacetoaldehyde 
• 102854-62-6 4-trifluoromethyl-2-trimethylsyloxyfuran 

Downstream Products

• 100906-01-2 4-trifluoromethyl-5-(2-benzyloxy-1-methoxymethoxy)ethyl-2(5H)-furanone 
• 100922-49-4 5-[2-Benzyloxy-eth-(Z)-ylidene]-4-trifluoromethyl-5H-furan-2-one 
• 102854-72-8 (+/-)-isopropyl 6-O-benzyl-3-trifluoromethyl-5-O-methoxymethyl-α-gulofuranoside 
• 102854-72-8 (+/-)-isopropyl 6-O-benzyl-3-trifluoromethyl-5-O-methoxymethyl-β-talofuranoside 
• 102854-70-6 trans-4-trifluoromethyl-5-(2-benzyloxy-1-methoxymethoxy)ethyl-2-isopropyloxy-2,5-dihydrofuran 
• 102854-70-6 cis-4-trifluoromethyl-5-(2-benzyloxy-1-methoxymethoxy)ethyl-2-isopropyloxy-2,5-dihydrofuran 
• 102854-69-3 (S)-5-((S)-2-Benzyloxy-1-methoxymethoxy-ethyl)-4-trifluoromethyl-2,5-dihydro-furan-2-ol 

Relevant academic research and scientific papers

Studies on Organic Fluorine Compounds. XLVII. Synthesis of Trifluoromethylated Sugars through the Aldol Reaction of 2-Trimethylsilyloxy-4-trifluoromethylfuran

Lewis acid-catalyzed aldol condensation of 2-trimethylsilyloxy-4-trifluoromethylfuran (2a) with aldehydes was found to proceed in a regio- and diastereoselective manner to give the 5-substituted 4-trifluoromethyl-2(5H)-furanone (4) in good yield.The aldol