1009093-60-0

Basic information

• Product Name: 3-BROMO-5-FLUORO-2-METHOXYBENZALDEHYDE
• Synonyms: 3-BROMO-5-FLUORO-2-METHOXYBENZALDEHYDE
• CAS NO: 1009093-60-0
• Molecular Formula: C₈H₆BrFO₂
• Molecular Weight: 233.0344432
• Mol File: 1009093-60-0.mol

Chemical Properties

• Boiling Point: 289.8±35.0 °C(Predicted)
• Appearance: /
• Density: 1.601±0.06 g/cm3(Predicted)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 3-BROMO-5-FLUORO-2-METHOXYBENZALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-BROMO-5-FLUORO-2-METHOXYBENZALDEHYDE(1009093-60-0)
• EPA Substance Registry System: 3-BROMO-5-FLUORO-2-METHOXYBENZALDEHYDE(1009093-60-0)

Safety Data

• Hazard Codes: Xi
• Statements: 36
• Safety Statements: 26
• Hazardous Substances Data: 1009093-60-0(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Synthesis:
3-Bromo-5-Fluoro-2-Methoxybenzaldehyde is used as a key intermediate in the synthesis of pharmaceuticals for its ability to contribute to the development of new drugs. Its unique molecular structure allows for the creation of a variety of medicinal compounds with potential therapeutic applications.
Used in Organic Chemistry:
In the field of organic chemistry, 3-Bromo-5-Fluoro-2-Methoxybenzaldehyde is utilized as a versatile building block for the synthesis of various organic compounds. Its reactivity and functional groups make it suitable for a wide range of chemical reactions, contributing to the advancement of organic synthesis techniques.
Used in Medicinal Chemistry Research:
3-Bromo-5-Fluoro-2-Methoxybenzaldehyde is employed as a valuable compound in medicinal chemistry research. Its biological activities and potential as a drug development building block make it an essential tool for exploring new therapeutic agents and understanding their mechanisms of action.
Used in Chemical Reactions:
As a chemical intermediate, 3-Bromo-5-Fluoro-2-Methoxybenzaldehyde is used in various chemical reactions to produce a range of products. Its unique properties and reactivity enable the synthesis of diverse compounds, expanding the scope of chemical research and development.

Upstream product

• 496-69-5 2-bromo-4-fluoro-phenol 
• 178546-34-4 3-bromo-5-fluoro-2-hydroxybenzaldehyde 
• 74-88-4 methyl iodide 

Downstream Products

• 1009093-61-1 C₈H₉BrFNO₂ 
• 1009093-62-2 C₁₁H₁₁BrFNO₄ 
• 1009093-64-4 C₁₅H₁₇BrFNO₅ 
• 1009093-63-3 C₂₁H₃₁BrFNO₅Si 
• 1009093-65-5 C₂₅H₃₆BrFN₂O₅ 
• 1009093-66-6 C₃₄H₄₆FN₃O₇ 
• 1009092-61-8 C₄₅H₆₂FN₅O₆ 

Relevant articles and documents

Redox-Neutral Coupling between Two C(sp3)?H Bonds Enabled by 1,4-Palladium Shift for the Synthesis of Fused Heterocycles

The intramolecular coupling of two C(sp3)?H bonds to forge a C(sp3)?C(sp3) bond is enabled by 1,4-Pd shift from a trisubstituted aryl bromide. Contrary to most C(sp3)?C(sp3) cross-dehydrogenative couplings, this reaction operates under redox-neutral conditions, with the C?Br bond acting as an internal oxidant. Furthermore, it allows the coupling between two moderately acidic primary or secondary C?H bonds, which are adjacent to an oxygen or nitrogen atom on one side, and benzylic or adjacent to a carbonyl group on the other side. A variety of valuable fused heterocycles were obtained from easily accessible ortho-bromophenol and aniline precursors. The second C?H bond cleavage was successfully replaced with carbonyl insertion to generate other types of C(sp3)-C(sp3) bonds.

Compounds and Methods for Inhibiting the Interaction of BCL Proteins with Binding Partners

The invention relates to isoxazolidine containing compounds that bind to bcl proteins and inhibit Bcl function. The compounds may be used for treating and modulating disorders associated with hyperproliferation, such as cancer.