100914-35-0 Usage
General Description
2-(4-nitro-1,3-dioxo-isoindolin-2-yl)-benzoic acid is a chemical compound with the molecular formula C16H9NO6. It is a yellow solid that is commonly used in organic synthesis and pharmaceutical research. 2-(4-nitro-1,3-dioxo-isoindolin-2-yl)-benzoic acid is a derivative of benzoic acid and contains a nitro group and an isoindolin-1,3-dione moiety. It has been studied for its potential therapeutic applications, including its anti-inflammatory and anti-cancer properties. Additionally, it has been used as a building block for the synthesis of pharmaceutical compounds and other organic molecules.
Check Digit Verification of cas no
The CAS Registry Mumber 100914-35-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,0,9,1 and 4 respectively; the second part has 2 digits, 3 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 100914-35:
(8*1)+(7*0)+(6*0)+(5*9)+(4*1)+(3*4)+(2*3)+(1*5)=80
80 % 10 = 0
So 100914-35-0 is a valid CAS Registry Number.
100914-35-0Relevant articles and documents
Method of inhibiting binding of nerve growth factor to p75 NTR receptor
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, (2008/06/13)
The present invention relates to compositions which inhibit the binding of nerve growth factor to the p75NTRcommon neurotrophin receptor and methods of use thereof. In one embodiment, the compound which inhibits binding of nerve growth factor to p75NTRcomprises, particularly when bound to nerve growth factor, at least two of the following: (1) a first electronegative atom or functional group positioned to interact with Lys34of nerve growth factor; (2) a second electronegative atom or functional group positioned to interact with Lys95of nerve growth factor; (3) a third electronegative atom or functional group positioned to interact with Lys88of nerve growth factor; (4) a fourth electronegative atom or functional group positioned to interact with Lys32of nerve growth factor; and (5) a hydrophobic moiety which interacts with the hydrophobic region formed by Ile31, Phe101and Phe86of nerve growth factor.
