TYR-CORTICOTROPIN RELEASING FACTOR HUMAN, RAT is a modified peptide hormone derived from the naturally occurring corticotropin-releasing factor (CRF). This modification involves the addition of a tyrosine molecule, which may enhance its activity or stability. It is produced in the hypothalamus and plays a pivotal role in the body's stress response system, known as the HPA axis, by stimulating the release of adrenocorticotropic hormone (ACTH) and cortisol. Furthermore, it is implicated in various physiological and behavioral processes, such as anxiety, depression, and addiction.
100915-92-2
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Basic information
- Product Name: TYR-CORTICOTROPIN RELEASING FACTOR HUMAN, RAT
- Synonyms: TYR-SER-GLU-GLU-PRO-PRO-ILE-SER-LEU-ASP-LEU-THR-PHE-HIS-LEU-LEU-ARG-GLU-VAL-LEU-GLU-MET-ALA-ARG-ALA-GLU-GLN-LEU-ALA-GLN-GLN-ALA-HIS-SER-ASN-ARG-LYS-LEU-MET-GLU-ILE-ILE-NH2;TYR-SER-GLU-GLU-PRO-PRO-ILE-SER-LEU-ASP-LEU-THR-PHE-HIS-LEU-LEU-ARG-GLU-VAL-LEU-GLU-MET-ALA-ARG-ALA-GLU-GLN-LEU-ALA-GLN-GLN-ALA-HIS-SER-ASN-ARG-LYS-LEU-MET-GLU-ILE-ILE-NH2 HUMAN, RAT;TYR-CORTICOTROPIN RELEASING FACTOR HUMAN, RAT;TYR-CRF (HUMAN, RAT);[TYR0]-CORTICOTROPIN RELEASING FACTOR, HUMAN, RAT;[TYR0]-CRF HUMAN, RAT;H-TYR-SER-GLU-GLU-PRO-PRO-ILE-SER-LEU-ASP-LEU-THR-PHE-HIS-LEU-LEU-ARG-GLU-VAL-LEU-GLU-GLU-MET-ALA-ARG-ALA-GLU-GLN-LEU-ALA-GLN-GLN-ALA-HIS-SER-ASN-ARG-LYS-LEU-MET-GLU-ILE-ILE-NH2;H-TYR-SER-GLU-GLU-PRO-PRO-ILE-SER-LEU-ASP-LEU-THR-PHE-HIS-LEU-LEU-ARG-GLU-VAL-LEU-GLU-MET-ALA-ARG-ALA-GLU-GLN-LEU-ALA-GLN-GLN-ALA-HIS-SER-ASN-ARG-LYS-LEU-MET-GLU-ILE-ILE-NH2
- CAS NO:100915-92-2
- Molecular Formula: C217H352N60O66S2
- Molecular Weight: 0
- EINECS: N/A
- Product Categories: N/A
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: /
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: −20°C
- Solubility: N/A
- CAS DataBase Reference: TYR-CORTICOTROPIN RELEASING FACTOR HUMAN, RAT(CAS DataBase Reference)
- NIST Chemistry Reference: TYR-CORTICOTROPIN RELEASING FACTOR HUMAN, RAT(100915-92-2)
- EPA Substance Registry System: TYR-CORTICOTROPIN RELEASING FACTOR HUMAN, RAT(100915-92-2)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany: 3
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 100915-92-2(Hazardous Substances Data)
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100915-92-2 Usage
Uses
Used in Pharmaceutical Industry:TYR-CORTICOTROPIN RELEASING FACTOR HUMAN, RAT is used as a therapeutic agent for targeting the HPA axis and modulating the body's stress response. Its application in this industry is aimed at developing treatments for stress-related disorders and conditions, such as anxiety, depression, and addiction.
Used in Research Applications:
TYR-CORTICOTROPIN RELEASING FACTOR HUMAN, RAT serves as a valuable research tool for studying the mechanisms underlying the stress response and its associated physiological and behavioral processes. It is utilized in laboratory settings to investigate the role of CRF in various conditions and to develop potential therapeutic interventions.
Used in Drug Development:
TYR-CORTICOTROPIN RELEASING FACTOR HUMAN, RAT is employed in the development of novel drugs targeting the HPA axis and related pathways. Its modified structure may offer advantages in terms of activity, stability, or specificity, making it a promising candidate for the creation of new therapeutic agents.
Used in Diagnostic Applications:
TYR-CORTICOTROPIN RELEASING FACTOR HUMAN, RAT can be utilized in diagnostic assays to measure the levels of CRF or its receptors in biological samples. This can aid in the identification of stress-related disorders and monitor the effectiveness of treatments.
Overall, TYR-CORTICOTROPIN RELEASING FACTOR HUMAN, RAT is a versatile molecule with potential applications in various industries, including pharmaceuticals, research, drug development, and diagnostics, due to its role in the body's stress response and its implications in various physiological and behavioral processes.
Check Digit Verification of cas no
The CAS Registry Mumber 100915-92-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,0,9,1 and 5 respectively; the second part has 2 digits, 9 and 2 respectively.Calculate Digit Verification of CAS Registry Number 100915-92:
(8*1)+(7*0)+(6*0)+(5*9)+(4*1)+(3*5)+(2*9)+(1*2)=92
92 % 10 = 2
So 100915-92-2 is a valid CAS Registry Number.
100915-92-2Upstream product
100915-92-2Downstream Products
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TYR-CORTICOTROPIN RELEASING FACTOR HUMAN, RAT
