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100927-09-1

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100927-09-1 Usage

General Description

Carbamic acid, [(1R)-1-cyanoethyl]-, 1,1-dimethylethyl ester (9CI) is a chemical compound with the formula C9H16N2O2. It is also known as tert-butyl (1R)-1-cyanoethylcarbamate and is commonly used as a reagent in organic chemistry. It is a colorless liquid with a faint odor and is insoluble in water but soluble in organic solvents. Carbamic acid, [(1R)-1-cyanoethyl]-, 1,1-dimethylethyl ester (9CI) is used in the production of pharmaceuticals and agrochemicals, and also as an intermediate in the synthesis of other organic compounds. It is important to handle this chemical with care and follow appropriate safety protocols due to its potential hazards if not handled properly.

Check Digit Verification of cas no

The CAS Registry Mumber 100927-09-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,0,9,2 and 7 respectively; the second part has 2 digits, 0 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 100927-09:
(8*1)+(7*0)+(6*0)+(5*9)+(4*2)+(3*7)+(2*0)+(1*9)=91
91 % 10 = 1
So 100927-09-1 is a valid CAS Registry Number.

100927-09-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 11, 2017

Revision Date: Aug 11, 2017

1.Identification

1.1 GHS Product identifier

Product name tert-butyl N-[(1R)-1-cyanoethyl]carbamate

1.2 Other means of identification

Product number -
Other names carbamic acid,(1-cyanoethyl)-,1,1-dimethylethyl ester

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:100927-09-1 SDS

100927-09-1Downstream Products

100927-09-1Relevant articles and documents

Synthesis of 3,5-disubstituted 1,2,4-oxadiazoles as peptidomimetic building blocks

Jakopin, ?iga,Ro?kar, Robert,Dolenc, Marija Sollner

, p. 1465 - 1468 (2007)

Twelve new 1,2,4-oxadiazole based compounds have been synthesized. Their structures contain a protected amine and a carboxyl or an ester group, and thus serve as potential peptidomimetic building blocks. The synthetic route is simple and mild conditions are used so that the chirality of the starting amino acids is retained.

BENZAMIDES OF PYRAZOLYL-AMINO-PYRIMIDINYL DERIVATIVES, AND COMPOSITIONS AND METHODS THEREOF

-

Paragraph 00442, (2020/07/07)

Provided is a novel class of orally and/or topically available, selective and potent JAK inhibitors as safe and effective therapeutics against various diseases and disorders. More particularly, provided are pharmaceutical composition of these compounds and methods of their preparation and use thereof.

Total syntheses of bacillamide C and neobacillamide A; Revision of their absolute configurations

Martinez, Veronica,Davyt, Danilo

, p. 1572 - 1575 (2014/01/06)

The enantiospecific syntheses of both enantiomers of bacillamide C and neobacillamide A are described, along with the measurement of their optical activities, leading to the revision of the proposed absolute configurations of these natural products.

Discovery, biological evaluation, and structure-activity relationship of amidine based sphingosine kinase inhibitors

Mathews, Thomas P.,Kennedy, Andrew J.,Kharel, Yugesh,Kennedy, Perry C.,Nicoara, Oana,Sunkara, Manjula,Morris, Andrew J.,Wamhoff, Brian R.,Lynch, Kevin R.,MacDonald, Timothy L.

experimental part, p. 2766 - 2778 (2010/09/04)

Sphingosine 1-phosphate (S1P), a potent phospholipid growth and trophic factor, is synthesized in vivo by two sphingosine kinases. Thus these kinases have been proposed as important drug targets for treatment of hyperproliferative diseases and inflammation. We report here a new class of amidine-based sphingosine analogues that are competitive inhibitors of sphingosine kinases exhibiting varying degrees of enzyme selectivity. These inhibitors display KI values in the submicromolar range for both sphingosine kinases and, in cultured vascular smooth muscle cells, decrease S1P levels and initiate growth arrest.

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