100929-53-1 Usage
Uses
Different sources of media describe the Uses of 100929-53-1 differently. You can refer to the following data:
1. Mu-opioid receptor-specific enkephalin analog
2. [D-Ala2, N-Me-Phe4, Gly5-ol]-Enkephalin acetate salt or DAMGO has been used:for use as a positive control in the assay of G-protein activation with μ-opioid receptor, to assay the inhibition of cAMP inhibition by DAMGO for the determination of the suppression of contraction by opioid receptors to determine whether the peripheral application of DAMGO suppresses the hypertonic saline (HS)-induced masseter nociception in slightly anaesthetized rats
General Description
[D-Ala2, N-Me-Phe4, Gly5-ol]-Enkephalin acetate salt or DAMGO is a full agonist of the μ-opioid receptor. μ-opioid receptor is encoded by the OPRM1 gene, which has a predominant expression in reward-processing areas of brain. It acts as a receptor for endogenous opioids such as β-endorphin, encephalin, as well as foreign opioids such as morphine, heroin, and methadone.
Biochem/physiol Actions
Enkephalin analog that is a selective agonist at μ-opioid receptors.
Check Digit Verification of cas no
The CAS Registry Mumber 100929-53-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,0,9,2 and 9 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 100929-53:
(8*1)+(7*0)+(6*0)+(5*9)+(4*2)+(3*9)+(2*5)+(1*3)=101
101 % 10 = 1
So 100929-53-1 is a valid CAS Registry Number.
InChI:InChI=1/C26H35N5O6.C2H4O2/c1-17(30-25(36)21(27)14-19-8-10-20(33)11-9-19)24(35)29-16-23(34)31(2)22(26(37)28-12-13-32)15-18-6-4-3-5-7-18;1-2(3)4/h3-11,17,21-22,32-33H,12-16,27H2,1-2H3,(H,28,37)(H,29,35)(H,30,36);1H3,(H,3,4)/t17-,21+,22+;/m1./s1
